Review
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World J Gastrointest Endosc. May 16, 2012; 4(5): 167-179
Published online May 16, 2012. doi: 10.4253/wjge.v4.i5.167
Endoscopic extraction of large common bile duct stones: A review article
Gerasimos Stefanidis, Christos Christodoulou, Spilios Manolakopoulos, Ram Chuttani
Gerasimos Stefanidis, Christos Christodoulou, Department of Gastroenterology, Athens Naval Hospital, 70 Deinokratous St, 115 21 Athens, Greece
Spilios Manolakopoulos, 2nd Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital of Athens, 114 Vas. Sophias Ave, 115 27 Athens, Greece
Ram Chuttani, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, United States
Author contributions: Stefanidis G designed, wrote and revised the paper; Christodoulou C reviewed the literature and wrote the paper; Manolakopoulos S reviewed the literature and revised the paper; Chuttani R revised the paper.
Correspondence to: Gerasimos Stefanidis, MD, Department of Gastroenterology, Athens Naval Hospital, 70 Deinokratous St, 115 21, Athens, Greece. stefanidis2001@yahoo.com
Telephone: +30-210-7261871 Fax: +30-210-7261368
Received: October 13, 2011
Revised: April 14, 2012
Accepted: April 27, 2012
Published online: May 16, 2012
Abstract

Since therapeutic endoscopic retrograde cholangiopancreatography replaced surgery as the first approach in cases of choledocolithiasis, a plethora of endoscopic techniques and devices appeared in order to facilitate rapid, safe and effective bile duct stones extraction. Nowadays, endoscopic sphincterotomy combined with balloon catheters and/or baskets is the routine endoscopic technique for stone extraction in the great majority of patients. Large common bile duct stones are treated conventionally with mechanical lithotripsy, while the most serious complication of the procedure is “basket and stone impaction” that is predominately resolved surgically. In cases of difficult, impacted, multiple or intrahepatic stones, more sophisticated procedures have been used. Electrohydraulic lithotripsy and laser lithotripsy are performed using conventional mother-baby scope systems, ultra-thin cholangioscopes, thin endoscopes and ultimately using the novel single use, single operator SpyGlass Direct Visualization System, in order to deliver intracorporeal shock wave energy to fragment the targeted stone, with very good outcomes. Recently, large balloon dilation after endoscopic sphincterotomy confirmed its effectiveness in the extraction of large stones in a plethora of trials. When compared with mechanical lithotripsy or with balloon dilation alone, it proved to be superior. Moreover, dilation is an ideal alternative in cases of altered anatomy where access to the papilla is problematic. Endoscopic sphincterotomy followed by large balloon dilation represents the onset of a new era in large bile duct stone extraction and the management of “impaction” because it seems that is an effective, inexpensive, less traumatic, safe and easy method that does not require sophisticated apparatus and can be performed widely by skillful endoscopists. When complete extraction of large stones is unsuccessful, the drainage of the common bile duct is mandatory either for bridging to the final therapy or as a curative therapy for very elderly patients with short life expectancy. Placing of more than one plastic endoprostheses is better while the administration of Ursodiol is ineffective. The great majority of patients with large stones can be treated endoscopically. In cases of unsuccessful stone extraction using balloons, baskets, mechanical lithotripsy, electrohydraulic or laser lithotripsy and large balloon dilation, the patient should be referred for extracorporeal shock wave lithotripsy or a percutaneous approach and finally surgery.

Keywords: Large bile duct stones; Endoscopic sphincterotomy; Papillary balloon dilation; Large papillary balloon dilation; Mechanical lithotripsy; Electrohydraulic lithotripsy; Laser lithotripsy