Brief Article
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2012; 4(2): 33-37
Published online Feb 16, 2012. doi: 10.4253/wjge.v4.i2.33
Blue mode does not offer any benefit over white light when calculating Lewis score in small-bowel capsule endoscopy
Anastasios Koulaouzidis, Sarah Douglas, John N Plevris
Anastasios Koulaouzidis, Sarah Douglas, John N Plevris, Endoscopy Unit, Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, Scotland, United Kingdom
John N Plevris, Medical School, The University of Edinburgh, Edinburgh EH16 4SA, Scotland, United Kingdom
Author contributions: Koulaouzidis A, Douglas S and Plevris JN contributed equally to the conception, design, acquisition of data, analysis and interpretation of data; Koulaouzidis A and Plevris JN contributed to the drafting and critical review of the article for important intellectual content.
Correspondence to: Dr., Anastasios Koulaouzidis, MD, MRCP, FEBG, Endoscopy Unit, Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, Scotland, United Kingdom. akoulaouzidis@hotmail.com
Telephone: +44-1312421126 Fax: +44-1312421618
Received: August 30, 2011
Revised: January 16, 2012
Accepted: February 6, 2012
Published online: February 16, 2012
Abstract

AIM: To check the usefulness of blue mode (BM) review in lewis score (LS) calculation, by comparing it with respective LS results obtained by white light (WL) small-bowel capsule endoscopy (SBCE) review and mucosal inflammation as reflected by faecal calprotectin (FC) levels, considered as ‘gold standard’ for this study.

METHODS: Computational analysis of our SBCE database to identify patients who underwent SBCE with PillCam® and had FC measured within a 30-day period from their test. Only patients with prior colonoscopy were included, to exclude any colon pathology-associated FC rise. Each small bowel tertile was reviewed (viewing speed 8 fps) with WL and BM, in a back-to-back mode, by a single experienced reviewer. LS were calculated after each WL and BM reviews. Pearson rank correlation (rho, r) statistic was applied.

RESULTS: Twenty-seven (n = 27, 20F/7M) patients were included. Thirteen (n = 13) had SBCE with PillCam®SB1, and the remainder (n = 14) with PillCam®SB2. The median level of FC in this cohort was 125 μg/g. LS (calculated in WL SBCE review) correlation with FC levels was r = 0.490 (P = 0.01), while for BM review and LS correlation with FC was r = 0.472 (P = 0.013).

CONCLUSION: Although BM is believed to enhance mucosal details i.e., small mucosal breaks, it did not perform better than WL in the calculation of LS in our cohort.

Keywords: Capsule endoscopy, Lewis score, PillCam, Blue mode, Rapid