Brief Article
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World J Gastrointest Endosc. Dec 16, 2012; 4(12): 556-560
Published online Dec 16, 2012. doi: 10.4253/wjge.v4.i12.556
Efficacy of ankaferd blood stopper application on non-variceal upper gastrointestinal bleeding
Gokhan Gungor, M Hakan Goktepe, Murat Biyik, Ilker Polat, Tuncer Tuna, Huseyin Ataseven, Ali Demir
Gokhan Gungor, Selcuk University, Meram School of Medicine, Gastroenterology Department, Meram, 42080 Konya, Turkey
M Hakan Goktepe, Ilker Polat, Tuncer Tuna, Selcuk University Meram Faculty of Medicine, Internal Medicine Konya, 42080 Konya, Turkey
Murat Biyik, Huseyin Ataseven, Ali Demir, Selcuk University Meram Faculty of Medicine, Gastroenterology, 42080 Konya, Turkey
Author contributions: Gungor G, Goktepe MH and Polat I performed the majority of experiments; Biyik M and Tuna T helped to write the article and did the language editing; Ataseven H and Demir A designed the study.
Correspondence to: Gokhan Gungor, MD, Selcuk University, Meram School of Medicine, Gastroenterology Department, Meram, 42080 Konya, Turkey. drgokhangungor@hotmail.com
Telephone: +90-332-2237121 Fax: +90-332-2237121
Received: December 23, 2011
Revised: September 5, 2012
Accepted: October 20, 2012
Published online: December 16, 2012
Abstract

AIM: To prospectively assess the hemostatic efficacy of the endoscopic topical use of ankaferd blood stopper (ABS) in active non-variceal upper gastrointestinal system (GIS) bleeding.

METHODS: Endoscopy was performed on 220 patients under suspiciency of GIS bleeding. Patients with active non-variceal upper gastrointestinal bleeding (NVUGIB) with a spurting or oozing type were included. Firstly, 8-10 cc of isotonic saline was sprayed to bleeding lesions. Then, 8 cc of ABS was applied on lesions in which bleeding continued after isotonic saline application. The other endoscopic therapeutic methods were applied on the lesions in which the bleeding did not stop after ABS.

RESULTS: Twenty-seven patients had an active NVUGIB with a spurting or oozing type and 193 patients were excluded from the study since they did not have non-variceal active bleeding. 8 cc of ABS was sprayed on to the lesions of 26 patients whose bleeding continued after isotonic saline and in 19 of them, bleeding stopped after ABS. Other endoscopic treatment methods were applied to the remaining patients and the bleeding was stopped with these interventions in 6 of 7 patients.

CONCLUSION: ABS is an effective method on NVUGIB, particularly on young patients with no coagulopathy. ABS may be considered as part of a combination treatment with other endoscopic methods.

Keywords: Ankaferd blood stopper; Non-variceal upper gastrointestinal bleeding; Endoscopic treatment