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World J Gastrointest Endosc. Sep 16, 2010; 2(9): 305-307
Published online Sep 16, 2010. doi: 10.4253/wjge.v2.i9.305
Capsule endoscopy: Future horizons
Zvi Fireman
Zvi Fireman, Department of Gastroenterology, Hillel-Yaffe Medical Center, Hadera 38100, Israel
Zvi Fireman, Faculty of Medicine, The Technion - Institute of Technology, The Rappaport Faculty of Medicine, Haifa 31096, Israel
Author contribution: Fireman Z contributed solely to this paper.
Correspondence to: Zvi Fireman, MD, Head, Department of Gastroenterology, Hillel Yaffe Medical Center, PO Box 169, Hadera 38100, Israel. fireman@hy.health.gov.il
Telephone: +972-4-6304480 Fax: +972-4-6304408
Received: May 4, 2010
Revised: July 4, 2010
Accepted: July 11, 2010
Published online: September 16, 2010
Abstract

Capsule endoscopy (CE) was launched at the beginning of this millennium and has since become a well established methodology for evaluating the entire small bowel for manifold pathologies. CE far exceeded early expectations by providing a tool for establishing the correct diagnosis for elusive gastrointestinal (GI) conditions such as obscure GI bleeding, Crohn’s disease, polyposis syndrome and others. Contemporary CE, like radiology, gives results that can only be read, unlike conventional endoscopic procedures which enable concomitant biopsy when indicated. This is one of the major limitations of the technique. The ideal CE should improve the quality of the image and have a faster frame rate than the currently available one. There should be a therapeutic capsule capable of performing a biopsy, aspirating fluid, delivering drugs as well as measuring the motility of the small bowel wall. Another major leap forward would be the capability of remote control of the capsule’s movement in order to navigate it to reach designated anatomical areas for carrying out a variety of therapeutic options. Technology for improving the capability of the future generation capsule is almost within grasp and it would not be surprising to witness the realization of these giant steps within the coming decade.

Keywords: Capsule endoscopy; Small bowel; Therapeutic capsule; Ideal capsule; Biopsy; Navigation