Zhang YJ, Yuan MX, Wen W, Jian Y, Zhang CM, Yuan J, He L. Endoscopic full-thickness resection of rectal schwannoma: A case report. World J Gastrointest Endosc 2025; 17(2): 102075 [DOI: 10.4253/wjge.v17.i2.102075]
Corresponding Author of This Article
Meng-Xia Yuan, Department of Digestive Diseases, Chengdu Second People’s Hospital, No. 10 Qingyun South Street, Chengdu 610000, Sichuan Province, China. 1062274198@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Feb 16, 2025; 17(2): 102075 Published online Feb 16, 2025. doi: 10.4253/wjge.v17.i2.102075
Endoscopic full-thickness resection of rectal schwannoma: A case report
Ying-Jie Zhang, Meng-Xia Yuan, Wu Wen, Yi Jian, Chuan-Ming Zhang, Jing Yuan, Lin He
Ying-Jie Zhang, Meng-Xia Yuan, Wu Wen, Yi Jian, Chuan-Ming Zhang, Jing Yuan, Department of Digestive Diseases, Chengdu Second People’s Hospital, Chengdu 610000, Sichuan Province, China
Lin He, Department of Pathology, Chengdu Second People’s Hospital, Chengdu 610000, Sichuan Province, China
Author contributions: All authors made significant contributions to the manuscript; Jian Y conceived the overall treatment plan for the patient; Yuan J led the postoperative patient follow-up; Zhang CM re-examined the patient’s colonoscopy; Zhang YJ, Wen W, and Yuan MX were involved in material preparation, data collection, and image analysis; He L made the postoperative pathological tumor diagnosis; Zhang YJ wrote the first draft of the manuscript; All authors read and approved the final manuscript.
Supported by Chengdu Key Technology Innovation R&D Projects (In the Field of Population Health) in the 2023, No. 2022-YF05-02120-SN.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng-Xia Yuan, Department of Digestive Diseases, Chengdu Second People’s Hospital, No. 10 Qingyun South Street, Chengdu 610000, Sichuan Province, China. 1062274198@qq.com
Received: October 11, 2024 Revised: December 6, 2024 Accepted: January 18, 2025 Published online: February 16, 2025 Processing time: 124 Days and 21.9 Hours
Abstract
BACKGROUND
Rectal schwannoma (RS) is a rare subtype of schwannoma that presents diagnostic challenges owing to its clinical rarity. The absence of typical symptoms, specific signs, and distinctive radiographic findings often hinders clinicians from reaching a definitive diagnosis before surgical intervention. Herein, we report a case of RS who underwent complete resection through endoscopic full-thickness resection (EFTR) and discuss the clinical, imaging, and pathological features for differential diagnosis.
CASE SUMMARY
A 71-year-old Chinese woman presented to our outpatient clinic with a 4-year history of a rectal mucosal mass for a follow-up surveillance colonoscopy. A neurogenic tumor with extraluminal growth was considered based on the imaging findings. Resection was required, and an EFTR was performed. On endoscopic exploration, a smooth surface extruding mass was identified at the rectum. The patient was discharged 48 hours after the operation without infection or bleeding. Based on the pathological and immunohistochemical findings of the resected mass, a rectal benign schwannoma was diagnosed. The patient did not undergo any adjuvant therapy. Nearly one year later, a follow-up surveillance colonoscopy and an abdominal and pelvic plain plus enhancement scan were performed, and no tumor recurrence or metastasis was noted.
CONCLUSION
EFTR is safe and effective for resecting gastrointestinal stromal tumors, especially those with extraluminal growth and no lymph node involvement.
Core Tip: This report highlights a rare case of rectal schwannoma that was not identified before resection but was successfully treated with endoscopic full-thickness resection alone, without the need for additional therapy. Our experience suggests that this technique may be a simple and effective treatment for colorectal submucosal tumors that are difficult to diagnose preoperatively, especially when there is no lymph node involvement.
