Yang N, Liu Z, Jin T, Xin HW, Gu L, Zheng Y, Zhou HX, Li N, Liu XJ. Esophageal ulcer and multisystem inflammatory syndrome after COVID-19: A case report. World J Gastrointest Endosc 2024; 16(8): 483-488 [PMID: 39155996 DOI: 10.4253/wjge.v16.i8.483]
Corresponding Author of This Article
Ning Li, MM, Attending Doctor, Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital University of Medical Science, No. 8 Gongrentiyuchang South Road, Chaoyang District, Beijing 100020, China. ning0116@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Aug 16, 2024; 16(8): 483-488 Published online Aug 16, 2024. doi: 10.4253/wjge.v16.i8.483
Esophageal ulcer and multisystem inflammatory syndrome after COVID-19: A case report
Ni Yang, Zhen Liu, Tong Jin, Hai-Wei Xin, Li Gu, Yue Zheng, Hui-Xing Zhou, Ning Li, Xin-Juan Liu
Ni Yang, Zhen Liu, Tong Jin, Hai-Wei Xin, Ning Li, Xin-Juan Liu, Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China
Li Gu, Department of Infectious Diseases and Clinical Microbiology, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China
Yue Zheng, Department of Surgical Intensive Care Unit, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China
Hui-Xing Zhou, Department of Hematology, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China
Author contributions: Yang N, Li N, Liu Z, Jin T and Liu XJ managed the patient; Xin HW performed gastroscopy; Zhou HX performed bone marrow aspiration; Gu L and Zheng Y offered opinions on diagnosis and treatment; Yang N performed manuscript writing; Li N and Liu XJ revised this article; All authors contributed to the paper and approved the submitted version.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: All authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning Li, MM, Attending Doctor, Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital University of Medical Science, No. 8 Gongrentiyuchang South Road, Chaoyang District, Beijing 100020, China. ning0116@163.com
Received: May 21, 2024 Revised: June 26, 2024 Accepted: July 3, 2024 Published online: August 16, 2024 Processing time: 72 Days and 14.2 Hours
Abstract
BACKGROUND
Multisystem inflammatory syndrome in adults (MIS-A) is a rare but severe disease occurring several weeks after severe acute respiratory syndrome coronavirus 2 infection. It develops in adults with inflammation of different organs including the gastrointestinal tract, heart, kidneys, skin and hematopoietic system.
CASE SUMMARY
We present a 58-year-old Chinese man diagnosed with MIS-A. His chief complaints were fever, generalized fatigue and anorexia, accompanied with rashes on his back. Further examination showed cardiac, renal and liver injury. He had melena and gastroscopy indicated esophageal ulcer and severe esophagitis. Repeated blood and sputum culture did not show growth of bacteria or fungi. Antibiotic treatment was stopped due to unsatisfactory performance. His condition improved after prednisone and other supportive treatment.
CONCLUSION
Gastrointestinal involvement in MIS-A is not uncommon. Intestinal involvement predominates, and esophageal involvement is rarely reported. Esophageal ulcer with bleeding could also be a manifestation of MIS-A.
Core Tip: Multisystem inflammatory syndrome in adults (MIS-A) is a rare but severe disease occurring several weeks after severe acute respiratory syndrome coronavirus 2 infection. We present a 58-year-old Chinese man diagnosed with MIS-A who had multiple organ damage. The patient had melena and gastroscopy indicated esophageal ulcer and severe esophagitis. His condition improved after prednisone and other supportive treatment. Clinicians should take MIS-A into consideration when they face unexplained inflammation and multiorgan damage. Gastrointestinal involvement in MIS-A is not uncommon. Intestinal involvement predominates, and esophageal involvement is rarely reported.
