Alnajjar A, Alfadda A, Alqaraawi AM, Alajlan B, Atallah JP, AlHussaini HF. Pleomorphic leiomyosarcoma of the maxilla with metastasis to the colon: A case report. World J Gastrointest Endosc 2024; 16(6): 361-367 [DOI: 10.4253/wjge.v16.i6.361]
Corresponding Author of This Article
Abdulrahman Alfadda, FRCP (C), MBBS, MD, Associate Professor, Doctor, Section of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital & Research Centre, Al Mathar Ash Shamali, Riyadh 11211, Saudi Arabia. abalfadda@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Jun 16, 2024; 16(6): 361-367 Published online Jun 16, 2024. doi: 10.4253/wjge.v16.i6.361
Pleomorphic leiomyosarcoma of the maxilla with metastasis to the colon: A case report
Asma Alnajjar, Abdulrahman Alfadda, Abdullah Mohammad Alqaraawi, Bader Alajlan, Jean Paul Atallah, Hussah Fahad AlHussaini
Asma Alnajjar, Abdulrahman Alfadda, Abdullah Mohammad Alqaraawi, Bader Alajlan, Section of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia
Jean Paul Atallah, Department of Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia
Hussah Fahad AlHussaini, Department of Pathology, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia
Author contributions: Alqaraawi AM, Alfadda A, and Alajlan B proposed the idea of reporting this case; Alqaraawi AM and Alnajjar A were responsible for performing colonoscopy; Alfadda A assisted in removing the ascending colon polyp; Atallah JP was the patient’s primary oncologist; Atallah JP and Alnajjar A collected the data; Alhussaini HF provided pathology slides with reports of the findings; Alnajjar A was responsible for writing the manuscript; Alfadda A, Alqaraawi AM, and Alajlan B were responsible for revising and editing the manuscript, conceptualization, and supervision; and all authors have reviewed the literature review, and read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abdulrahman Alfadda, FRCP (C), MBBS, MD, Associate Professor, Doctor, Section of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital & Research Centre, Al Mathar Ash Shamali, Riyadh 11211, Saudi Arabia. abalfadda@gmail.com
Received: March 16, 2024 Revised: April 26, 2024 Accepted: May 17, 2024 Published online: June 16, 2024 Processing time: 89 Days and 14.3 Hours
Abstract
BACKGROUND
Pleomorphic leiomyosarcomas make up around 8.6% of all leiomyosarcomas. They behave aggressively and often have poor prognoses. They can affect the gastrointestinal tract and retroperitoneum. To date, pleomorphic leiomyosarcoma involving the mesocolon have been reported in nine patients.
CASE SUMMARY
The patient was a 44-year-old man with a history of pleomorphic leiomyosarcoma of the left maxilla with metastasis to the lung and liver. His most recent positron emission tomography-computed tomography (PET-CT) scan showed uptake in the ascending and transverse colons. A colonoscopy revealed a 5.0 cm × 3.5 cm × 3.0 cm pedunculated polyp in the ascending colon. The polyp was removed using hot snare polypectomy technique and retrieved with Rothnet. Histopathologic examination of the polyp showed a metastatic pleomorphic leiomyosarcoma.
CONCLUSION
Uptake(s) on PET-CT in a patient with pleomorphic leiomyosarcoma should raise suspicion for metastasis.
Core Tip: Pleomorphic leiomyosarcomas make up around 8.6% of all leiomyosarcomas. They behave aggressively and often have poor prognoses. They can affect the gastrointestinal tract and retroperitoneum. To date, pleomorphic leiomyosarcomas involving the mesocolon have been reported in nine patients. The present study describes a 44-year-old man with a history of left maxillary pleomorphic leiomyosarcoma. Colonoscopy identified an ascending colon polyp, which was confirmed to be a metastasis of the maxillary leiomyosarcoma by histopathological examination and immunohistochemical staining.
