George NM, Rajesh NA, Chitrambalam TG. Acute pancreatitis following endoscopic ampullary biopsy: A case report. World J Gastrointest Endosc 2023; 15(8): 540-544 [PMID: 37663115 DOI: 10.4253/wjge.v15.i8.540]
Corresponding Author of This Article
Nidhi Mariam George, MBBS, Doctor, Department of General Surgery, SRM Medical College Hospital and Research Centre, Chennai-Theni Highway, Chennai 603203, Tamil Nadu, India. drnidhigeorge@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nidhi Mariam George, Tharun Ganapathy Chitrambalam, Department of General Surgery, SRM Medical College Hospital and Research Centre, Chennai 603203, Tamil Nadu, India
Nanda Amarnath Rajesh, Department of Medical Gastroenterology, SRM Medical College Hospital and Research Centre, Chennai 6030203, India
Author contributions: George NM, Rajesh NA, and Chitrambalam TG contributed equally to this work; George NM assisted in patient care and wrote the manuscript, Rajesh NA and Chitrambalam TG assisted in data collection and manuscript revision; all authors have read and approved the final manuscript.
Informed consent statement: The patient and his wife have provided informed written consent for the publication of this case report.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nidhi Mariam George, MBBS, Doctor, Department of General Surgery, SRM Medical College Hospital and Research Centre, Chennai-Theni Highway, Chennai 603203, Tamil Nadu, India. drnidhigeorge@gmail.com
Received: January 4, 2023 Peer-review started: January 4, 2023 First decision: April 13, 2023 Revised: April 18, 2023 Accepted: July 17, 2023 Article in press: July 17, 2023 Published online: August 16, 2023 Processing time: 217 Days and 11.3 Hours
Abstract
BACKGROUND
Endoscopic biopsy is mandatory for the diagnosis of malignant and premalignant ampullary tumours. The commonly reported inadvertent complications following routine mucosal biopsy include perforation and haemorrhage. Acute pancreatitis is an extremely rare complication following this procedure.
CASE SUMMARY
This report details the case of a 59-year-old man who underwent biopsy of the ampulla for a suspected periampullary tumour. Following the procedure, the patient presented with symptoms of acute pancreatitis which was substantiated by laboratory and radiological investigations. He was conservatively managed and discharged following complete resolution of symptoms.
CONCLUSION
This case report serves to highlight the importance of this potential complication following routine endoscopic biopsy of the ampulla.
Core Tip: Gastrointestinal endoscopic procedures are relatively safe and are being routinely performed with the advent of minimally invasive procedures. Acute pancreatitis is an extremely uncommon complication following endoscopic ampullary biopsy. It is important for endoscopists to be mindful of this untoward complication with appropriate post-procedure monitoring and support.