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World J Gastrointest Endosc. Feb 16, 2023; 15(2): 19-31
Published online Feb 16, 2023. doi: 10.4253/wjge.v15.i2.19
Endoscopic treatment and management of rectal neuroendocrine tumors less than 10 mm in diameter
Xiao-Xin Ma, Li-Sheng Wang, Luo-Lin Wang, Ting Long, Zheng-Lei Xu
Xiao-Xin Ma, Li-Sheng Wang, Luo-Lin Wang, Zheng-Lei Xu, Department of Gastroenterology, Shenzhen People’s Hospital, the 2nd Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China
Ting Long, Department of Pathology, Shenzhen People’s Hospital, the 2nd Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China
Author contributions: Xu ZL conceived the idea for the manuscript; Ma XX wrote the first draft of the manuscript; Long T searched part of the information; Wang LS reviewed and revised the manuscript.
Conflict-of-interest statement: There is no conflict of interest in this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng-Lei Xu, MD, Chief Doctor, Department of Gastroenterology, Shenzhen People’s Hospital, the 2nd Clinical Medical College of Jinan University, No. 1017 Dongmen North Road, Shenzhen 518000, Guangdong Province, China. 78249073@qq.com
Received: September 13, 2022
Peer-review started: September 13, 2022
First decision: October 30, 2022
Revised: November 19, 2022
Accepted: February 1, 2023
Article in press: February 1, 2023
Published online: February 16, 2023
Processing time: 152 Days and 20.9 Hours
Abstract

Rectal neuroendocrine tumors (rNETs) measuring less than 10 mm in diameter are defined as small rNETs. Due to the low risk of distant invasion and metastasis, endoscopic treatments, including modified endoscopic mucosal resection, endoscopic submucosal dissection, and other transanal surgical procedures, are effective. This review article proposes a follow-up plan according to the size and histopathology of the tumor after operation.

Keywords: Rectal neuroendocrine tumors; Endoscopic; Endoscopic submucosal dissection; Endoscopic mucosal resection

Core Tip: Rectal neuroendocrine tumors (rNETs) measuring less than 10 mm in diameter are defined as small rNETs. Due to the low risk of distant invasion and metastasis, endoscopic treatments, including modified endoscopic mucosal resection, endoscopic submucosal dissection, and other transanal surgical procedures, are effective. This review article proposes a follow-up plan according to the size and histopathology of the tumor after operation.