1
|
Iwamuro M, Yoshikawa T, Kamio T, Hirata S, Matsueda K, Kametaka D, Otsuka M. Temporal changes in computed tomography findings of a persimmon bezoar: A case report. World J Clin Cases 2025; 13:103426. [DOI: 10.12998/wjcc.v13.i18.103426] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/25/2024] [Revised: 01/18/2025] [Accepted: 02/06/2025] [Indexed: 02/27/2025] Open
Abstract
BACKGROUND Gastric bezoars are masses of indigestible material that accumulate in the stomach, causing nausea, abdominal pain, and vomiting. Persimmon bezoars (diospyrobezoars), which comprise tannins and fibers from persimmons, are relatively rare but may cause significant gastric complications, including gastric outlet obstruction or ileus. Although computed tomography (CT) is a useful imaging tool, diagnosing bezoars can be challenging because their density is similar to that of food debris and gastric content.
CASE SUMMARY Here, we report the case of a 72-year-old woman with a persimmon bezoar that was diagnosed using serial CT imaging and confirmed by endoscopy. CT performed over several months revealed changes in the internal structure and density of the bezoar, suggesting progressive hardening. The patient had a history of a partial gastrectomy and excessive persimmon consumption, both of which are risk factors for bezoar formation. Endoscopic fragmentation of the bezoar successfully resolved symptoms.
CONCLUSION Gastric bezoars, particularly persimmon bezoars, present diagnostic challenges because of their variable imaging characteristics. Serial CT can document temporal changes in bezoar density, potentially reflecting changes in hardness. Early diagnosis and endoscopic treatment are essential for effective management, particularly in patients with predisposing factors. This case underscores the importance of considering bezoars in the differential diagnosis of gastric masses, and highlights the value of CT for monitoring changes in bezoar characteristics over time.
Collapse
Affiliation(s)
- Masaya Iwamuro
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Tomoki Yoshikawa
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Tomohiro Kamio
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Shoichiro Hirata
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Katsunori Matsueda
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Daisuke Kametaka
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| | - Motoyuki Otsuka
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
| |
Collapse
|
2
|
Shu J, Zhang H. Tennis ball cord combined with endoscopy for giant gastric phytobezoar: A case report. World J Clin Cases 2024; 12:3603-3608. [PMID: 38983432 PMCID: PMC11229917 DOI: 10.12998/wjcc.v12.i18.3603] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/07/2024] [Revised: 04/22/2024] [Accepted: 05/15/2024] [Indexed: 06/13/2024] Open
Abstract
BACKGROUND Due to the specificity of Chinese food types, gastric phytobezoars are relatively common in China. Most gastric phytobezoars can be removed by chemical enzyme lysis and endoscopic fragmentation, but the treatment for large phytobezoars is limited, and surgical procedures are often required for this difficult problem. CASE SUMMARY For giant gastric phytobezoars that cannot be dissolved and fragmented by conventional treatment, we have invented a new lithotripsy technique (tennis ball cord combined with endoscopy) for these phytobezoars. This non-interventional treatment was successful in a patient whose abdominal pain was immediately relieved, and the gastroscope-induced ulcer healed well 3 d after lithotripsy. The patient was followed-up for 8 wk postoperatively and showed no discomfort such as abdominal pain. CONCLUSION The combination of tennis ball cord and endoscopy for the treatment of giant gastric phytobezoars is feasible and showed high safety and effectiveness, and can be widely applied in hospitals of all sizes.
Collapse
Affiliation(s)
- Juan Shu
- Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, Hubei Province, China
| | - Heng Zhang
- Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, Hubei Province, China
| |
Collapse
|
3
|
Liu FG, Meng DF, Shen X, Meng D, Liu Y, Zhang LY. Coca-Cola consumption vs fragmentation in the management of patients with phytobezoars: A prospective randomized controlled trial. World J Gastrointest Endosc 2024; 16:83-90. [PMID: 38464817 PMCID: PMC10921151 DOI: 10.4253/wjge.v16.i2.83] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/28/2023] [Revised: 01/04/2024] [Accepted: 01/16/2024] [Indexed: 01/31/2024] Open
Abstract
BACKGROUND Gastric phytobezoars (GPBs) are very common in northern China. Combined therapy involving carbonated beverage consumption and endoscopic lithotripsy has been shown to be effective and safe. Existing studies on this subject are often case reports highlighting the successful dissolution of phytobezoars through Coca-Cola consumption. Consequently, large-scale prospective investigations in this domain remain scarce. Therefore, we conducted a randomized controlled trial to examine the effects of Coca-Cola consumption on GPBs. AIM To evaluate the impact of Coca-Cola on GPBs, including the dissolution rate, medical expenses, ulcer rate, and operation time. METHODS A total of 160 consecutive patients diagnosed with GPBs were allocated into two groups (a control group and an intervention group) through computer-generated randomization. Patients in the intervention group received a Coca-Cola-based regimen (Coca-Cola 2000-4000 mL per day for 7 d), while those in the control group underwent emergency fragmentation. RESULTS Complete dissolution of GPBs was achieved in 100% of the patients in the intervention group. The disparity in expenses between the control group and intervention group (t = 25.791, P = 0.000) was statistically significant, and the difference in gastric ulcer occurrence between the control group and intervention group (χ2 = 6.181, P = 0.013) was also statistically significant. CONCLUSION Timely ingestion of Coca-Cola yields significant benefits, including a complete dissolution rate of 100%, a low incidence of gastric ulcers, no need for fragmentation and reduced expenses.
Collapse
Affiliation(s)
- Fu-Guo Liu
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - De-Feng Meng
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Xia Shen
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Dan Meng
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Ying Liu
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Ling-Yun Zhang
- Endoscopy Center, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| |
Collapse
|
4
|
HanBin Z, Chunjiang Y, Yi W. Treatment of Children Trichobezoar a Retrospective Study of 11 Cases. KLINISCHE PADIATRIE 2022; 234:215-220. [PMID: 35359020 DOI: 10.1055/a-1689-0062] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 10/18/2022]
Abstract
PURPOSE The goal of this study to summarize the clinical features, treatment and prognosis of children trichobezoar, and to guide the clinical diagnosis and treatment. METHODS The clinical manifestations, auxiliary examination results, diagnosis and treatment process and family relationship of 11 cases of children with trichobezoar in our hospital were analyzed retrospectively. RESULTS 11 cases were female, 4 cases were divorced single parent family, and 2 case was left behind child. Six patients were admitted to hospital with sudden exacerbation of chronic abdominal pain, and four of them had recurrent vomiting. Five patients were admitted to hospital with acute abdominal pain, and 3 of them had vomiting symptoms; The weight of 1 case was lower than -2 SD, 4 cases were between -2 SD ~ -1 SD. 6 cases had palpable left upper abdominal mass with mild tenderness, 1 case only had left upper abdominal tenderness, 4 cases had no positive abdominal signs; The results of color Doppler ultrasonography in 8 children indicated the strong echo mass in the stomach, and 3 of them showed that the hyperechoic group extended to duodenum through pylorus. 7 cases had a tail end extending into the small intestine after removing the gastrolith during the operation. Four cases were found with jejunal perforation, 2 cases were treated with intestinal resection and anastomosis, and 2 cases were treated with intestinal repair. All the children were improved and discharged after operation. CONCLUSION For single parent families or left behind children with a history of chronic abdominal pain, vomiting and trichophilia, gastric hair stones should be highly suspected. For large hair stones in the stomach, they should be removed surgically. During the operation, the small intestine should be explored routinely to prevent the missed diagnosis of small intestinal perforation. Psychological guidance should be given to the children and their parents to prevent recurrence.
Collapse
Affiliation(s)
- Zhao HanBin
- Department of General Surgery & Neonatal Surgery, Liangjiang Wing, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics., Chongqing Medical University Affiliated Children's Hospital, Chongqing, China
| | - Yang Chunjiang
- Department of Ultrasound, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing Medical University Affiliated Children's Hospital, Chongqing, China
| | - Wang Yi
- Department of General Surgery & Neonatal Surgery, Liangjiang Wing, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics., Chongqing Medical University Affiliated Children's Hospital, Chongqing, China
| |
Collapse
|
5
|
Zhang FH, Ding XP, Zhang JH, Miao LS, Bai LY, Ge HL, Zhou YN. Acute esophageal obstruction caused by reverse migration of gastric bezoars: A case report. World J Clin Cases 2020; 8:3130-3135. [PMID: 32775396 PMCID: PMC7385598 DOI: 10.12998/wjcc.v8.i14.3130] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/28/2020] [Revised: 05/04/2020] [Accepted: 07/04/2020] [Indexed: 02/05/2023] Open
Abstract
BACKGROUND Bezoars can be found anywhere in the gastrointestinal tract. Esophageal bezoars are rare. Esophageal bezoars are classified as either primary or secondary. It is rarely reported that secondary esophageal bezoars caused by reverse migration from the stomach lead to acute esophageal obstruction. Guidelines recommend urgent upper endoscopy (within 24 h) for these impactions without complete esophageal obstruction and emergency endoscopy (within 6 h) for those with complete esophageal obstruction. Gastroscopy is regarded as the mainstay for the diagnosis and treatment of esophageal bezoars.
CASE SUMMARY A 59-year-old man was hospitalized due to nausea, vomiting and diarrhea for 2 d and sudden retrosternal pain and dysphagia for 10 h. He had a history of type 2 diabetes mellitus for 9 years. Computed tomography revealed dilated lower esophagus, thickening of the esophageal wall, a mass-like lesion with a flocculent high-density shadow and gas bubbles in the esophageal lumen. On gastroscopy, immovable brown bezoars were found in the lower esophagus, which led to esophageal obstruction. Endoscopic fragmentation was successful, and there were no complications. The symptoms of retrosternal pain and dysphagia disappeared after treatment. Mucosal superficial ulcers were observed in the lower esophagus. Multiple biopsy specimens from the lower esophagus revealed nonspecific findings. The patient remained asymptomatic, and follow-up gastroscopy 1 wk after endoscopic fragmentation showed no evidence of bezoars in the esophagus or the stomach.
CONCLUSION Acute esophageal obstruction caused by bezoars reversed migration from the stomach is rare. Endoscopic fragmentation is safe, effective and minimally invasive and should be considered as the first-line therapeutic modality.
Collapse
Affiliation(s)
- Fu-Hua Zhang
- Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
- Key Laboratory for Gastrointestinal Diseases, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
- Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Xiang-Ping Ding
- Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Jin-Hua Zhang
- Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Lian-Sheng Miao
- Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Ling-Yu Bai
- Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Hai-Lan Ge
- Department of Radiology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
| | - Yong-Ning Zhou
- Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
- Key Laboratory for Gastrointestinal Diseases, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
| |
Collapse
|
6
|
Lin L, Wang C, Wu J, Liu K, Liu H, Wei N, Lin W, Jiang G, Tai W, Su H. Gastric phytobezoars: the therapeutic experience of 63 patients in Northern China. REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS 2019; 112:12-15. [PMID: 31599640 DOI: 10.17235/reed.2019.6400/2019] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 12/20/2022]
Abstract
INTRODUCTION Sixty-three patients with gastric phytobezoars were reviewed. METHODS forty-eight (76.2%) patients received endoscopic combined with chemical therapies and 15 (23.8%) received only chemical therapy initially. Fifty-one (81.0%) patients achieved complete removal (only chemical therapy 14/15), while 12 (19.0%) received further endoscopic therapies. RESULTS finally, 62 (98.4%) patients achieved a complete removal. Considering only patients with combined treatment as a first approach, treatment success was associated with a softer phytobezoar consistency (p = 0.023). CONCLUSION in conclusion, most patients achieve a favorable outcome. Chemical therapy is useful in selected cases. Repeated endoscopic therapies may be needed in order to completely remove phytobezoars with a hard consistency.
Collapse
Affiliation(s)
- Lin Lin
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University, China
| | - Canghai Wang
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Jing Wu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Kuiliang Liu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Hong Liu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Nan Wei
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Wu Lin
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Guojun Jiang
- Beijing Shijitan Hospital, Capital Medical University
| | - Weiping Tai
- Gasstroenterology, Beijing Shijitan Hospital, Capital Medical University
| | - Hui Su
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| |
Collapse
|
7
|
Kurosu T, Tanabe S, Hasegawa R, Yano T, Wada T, Ishido K, Azuma M, Katada C, Koizumi W, Moriya H, Yamashita K. A giant trichobezoar extracted by laparoscopic and endoscopic cooperative surgery (LECS). Endosc Int Open 2018; 6:E1413-E1416. [PMID: 30505935 PMCID: PMC6264922 DOI: 10.1055/a-0732-4697] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/01/2018] [Accepted: 05/30/2018] [Indexed: 02/07/2023] Open
Abstract
A gastric bezoar is a mass that forms in the stomach. A giant gastric bezoar is particularly difficult to treat medically, and surgical therapy is selected. We describe our experience with a patient who had a giant gastric trichobezoar that was extracted by laparoscopic and endoscopic cooperative surgery (LECS) in accordance with the principles of LECS. The patient was a 32-year-old woman who presented at our hospital because of abdominal pain. Upper gastrointestinal endoscopy confirmed the presence of a giant gastric trichobezoar extending from the gastric cardia to the gastric angle. Because endoscopic removal was considered difficult, we extracted the giant gastric trichobezoar by LECS. The concurrent use of endoscopy was considered to allow a gastric bezoar to be extracted more safely and reliably than was previously possible.
Collapse
Affiliation(s)
- Takahiro Kurosu
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan,Corresponding author Takahiro Kurosu, MD Department of GastroenterologyKitasato University School of Medicine2-1-1 AsamizodaiMinami-kuSagamiharaKanagawa 252-0380Japan+81-42-7498690
| | - Satoshi Tanabe
- Research & Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Rikiya Hasegawa
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Takafumi Yano
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Takuya Wada
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Kenji Ishido
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Mizutomo Azuma
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Chikatoshi Katada
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Wasaburo Koizumi
- Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Hiromitsu Moriya
- Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| | - Keishi Yamashita
- Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
| |
Collapse
|
8
|
Iwamuro M, Saito S, Yoshioka M, Urata H, Ueda K, Yamamoto K, Okada H. A Magnesium Oxide Bezoar. Intern Med 2018; 57:3087-3091. [PMID: 29877289 PMCID: PMC6262705 DOI: 10.2169/internalmedicine.1124-18] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.9] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/03/2018] [Accepted: 04/03/2018] [Indexed: 01/01/2023] Open
Abstract
A 75-year-old Japanese woman presented with nausea and appetite loss. Computed tomography showed a radiopaque substance in the stomach. Esophagogastroduodenoscopy revealed bezoars in the stomach, which were endoscopically retrieved. The bezoars were mainly composed of magnesium and oxide. Although bezoar formation associated with magnesium oxide consumption is infrequently encountered, the present case indicates that pharmacobezoar should be considered among the differential diagnoses in patients who demonstrate a radiopaque mass in the digestive tract and have a history of magnesium oxide use.
Collapse
Affiliation(s)
- Masaya Iwamuro
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
| | - Shunsuke Saito
- Department of Internal Medicine, Okayama Saiseikai General Hospital, Japan
| | - Masao Yoshioka
- Department of Internal Medicine, Okayama Saiseikai General Hospital, Japan
| | - Haruo Urata
- Central Research Laboratory, Okayama University Medical School, Japan
| | - Kumiko Ueda
- Department of Pharmacy, Okayama University Hospital, Japan
| | - Kazuhide Yamamoto
- Department of Internal Medicine, Okayama Saiseikai General Hospital, Japan
| | - Hiroyuki Okada
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
| |
Collapse
|
9
|
Yamamoto M, Yamamoto K, Bian X, Guo Q, Sasaki T, Yamamoto F, Yamamoto H. Small Bowel Obstruction Caused by Dried Persimmon. Case Rep Gastroenterol 2018; 12:147-152. [PMID: 29805358 PMCID: PMC5968236 DOI: 10.1159/000488527] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/12/2018] [Accepted: 03/14/2018] [Indexed: 12/24/2022] Open
Abstract
Dried persimmon is a well-known dried fruit in Asian countries such as Japan, Korea, and China. Small bowel obstruction caused by phytobezoar is a rare but interesting pathogenesis that accounts for 2–4% of all small bowel obstructions. We present the case of an 87-year-old female who suffered from small bowel obstruction caused by ingestion of a huge, dried astringent persimmon. She was initially treated conservatively, but removal by enterotomy was performed after relief failed to be achieved with conservative therapy.
Collapse
Affiliation(s)
- Mami Yamamoto
- Department of Surgery, Yamamoto Memorial Hospital, Imari, Japan
| | | | - Xueyi Bian
- Department of Surgery, Yamamoto Memorial Hospital, Imari, Japan
| | - Qiang Guo
- Department of Surgery, Yamamoto Memorial Hospital, Imari, Japan
| | | | - Fumio Yamamoto
- Department of Surgery, Yamamoto Memorial Hospital, Imari, Japan
| | | |
Collapse
|
10
|
Small Bowel Obstruction Secondary to a Metamucil Bezoar: Case Report and Review of the Literature. Case Rep Surg 2017; 2017:2702896. [PMID: 29085697 PMCID: PMC5632449 DOI: 10.1155/2017/2702896] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2017] [Accepted: 08/17/2017] [Indexed: 12/29/2022] Open
Abstract
Bezoar-induced small bowel obstruction is a rare entity. It should be highly suspected in patients with gastric hypomotility disorders, psychiatric conditions, prior abdominal or bariatric surgery, or improper intake of medication. Their diagnosis is quite challenging and surgical exploration remains the best treatment of choice to ensure the viability of the small bowel tissue and relieve the obstruction. This is a case of a 48-year-old female with no previous abdominal surgery who presented with acute abdominal pain. The patient's history was remarkable for the daily ingestion of 1.5 teaspoons of Metamucil with minimal amount of water. Computed tomography scan demonstrated dilated small bowel loops and a transition zone at the level of the mid jejunum. On laparoscopy, the patient was found to have a hard mass in the mid jejunum amenable to gentle fragmentation and breakdown. Metamucil bezoars are due to the solidification of psyllium-based substances in the gastrointestinal tract. The usual management of small bowel obstruction induced by a bezoar is exploratory laparotomy with enterotomy and primary anastomosis. Laparoscopic intervention has gained popularity among surgeons with good outcome and lower morbidity. In this unusual case, the small bowel obstruction induced by the Metamucil bezoar was safely treated with laparoscopic fragmentation alone.
Collapse
|
11
|
Iwamuro M, Urata H, Higashi R, Nakagawa M, Ishikawa S, Shiraha H, Okada H. An Energy Dispersive X-ray Spectroscopy Analysis of Elemental Changes of a Persimmon Phytobezoar Dissolved in Coca-Cola. Intern Med 2016; 55:2611-2615. [PMID: 27629955 DOI: 10.2169/internalmedicine.55.6985] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/06/2022] Open
Abstract
To investigate the mechanism of phytobezoar dissolution by Coca-Cola(®), persimmon phytobezoar pieces removed from a 60-year-old Japanese woman were analyzed by energy dispersive X-ray spectroscopy. The amount of calcium significantly decreased after dissolution treatment using Coca-Cola(®), suggesting a potential contribution of calcium to dissolution mechanisms. Moreover, immersion in Coca-Cola(®) for 120 hours on the exterior surface revealed that Coca-Cola(®) did not permeate persimmon phytobezoars. This is the first study to investigate the mechanisms of persimmon phytobezoar permeability and dissolution induced by Coca-Cola(®).
Collapse
Affiliation(s)
- Masaya Iwamuro
- Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan
| | | | | | | | | | | | | |
Collapse
|
12
|
Vacante M, Alessandria I, Cataudella E, Fichera R, Malatino L. An Unexpected Cause of Marked Weight Loss Associated with Vomiting in an Adult Man: Gastric Phytobeozar. Eur J Case Rep Intern Med 2015; 3:000258. [PMID: 30755850 PMCID: PMC6346827 DOI: 10.12890/2015_000258] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/21/2015] [Accepted: 08/09/2015] [Indexed: 11/05/2022] Open
Abstract
Objectives We present the case of an edentulous 47-year-old farmer referred to our Department of Internal Medicine because of postprandial vomiting, hyporexia, asthenia and weight loss. He ate a mostly vegetarian diet. Materials and methods An oesophagogastroduodenoscopy revealed the presence of a phytobezoar at the level of the fundus and body of the stomach. Endoscopic fragmentation and removal of the phytobezoar were unsuccessful and the patient had to undergo open surgery. Results Recovery was uneventful and free of complications. Conclusion Phytobezoars should be taken into account in the differential diagnosis of unexplained vomiting and weight loss. LEARNING POINTS Bezoars are concretions of indigestible materials located in the gastrointestinal tract.Gastric phytobezoars may cause unexplained vomiting and weight loss even in young people.The diagnosis of phytobezoars may be complex and endoscopy is helpful in most cases.
Collapse
Affiliation(s)
- Marco Vacante
- Department of Internal Medicine, University of Catania, Ospedale Cannizzaro, Catania, Italy
| | - Innocenza Alessandria
- Department of Internal Medicine, University of Catania, Ospedale Cannizzaro, Catania, Italy
| | - Emanuela Cataudella
- Department of Internal Medicine, University of Catania, Ospedale Cannizzaro, Catania, Italy
| | - Rosangela Fichera
- Department of Internal Medicine, University of Catania, Ospedale Cannizzaro, Catania, Italy
| | - Lorenzo Malatino
- Department of Internal Medicine, University of Catania, Ospedale Cannizzaro, Catania, Italy
| |
Collapse
|
13
|
Iwamuro M, Okada H, Matsueda K, Inaba T, Kusumoto C, Imagawa A, Yamamoto K. Review of the diagnosis and management of gastrointestinal bezoars. World J Gastrointest Endosc 2015; 7:336-345. [PMID: 25901212 PMCID: PMC4400622 DOI: 10.4253/wjge.v7.i4.336] [Citation(s) in RCA: 184] [Impact Index Per Article: 18.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/06/2014] [Revised: 10/19/2014] [Accepted: 01/18/2015] [Indexed: 02/05/2023] Open
Abstract
The formation of a bezoar is a relatively infrequent disorder that affects the gastrointestinal system. Bezoars are mainly classified into four types depending on the material constituting the indigestible mass of the bezoar: phytobezoars, trichobezoars, pharmacobezoars, and lactobezoars. Gastric bezoars often cause ulcerative lesions in the stomach and subsequent bleeding, whereas small intestinal bezoars present with small bowel obstruction and ileus. A number of articles have emphasized the usefulness of Coca-Cola(®) administration for the dissolution of phytobezoars. However, persimmon phytobezoars may be resistant to such dissolution treatment because of their harder consistency compared to other types of phytobezoars. Better understanding of the etiology and epidemiology of each type of bezoar will facilitate prompt diagnosis and management. Here we provide an overview of the prevalence, classification, predisposing factors, and manifestations of bezoars. Diagnosis and management strategies are also discussed, reviewing mainly our own case series. Recent progress in basic research regarding persimmon phytobezoars is also briefly reviewed.
Collapse
|
14
|
Manning EP, Vattipallly V, Niazi M, Shah A. PhytobezoarInduced Small Bowel Obstruction in a Young Male with Virgin Abdomen. ACTA ACUST UNITED AC 2015; 5. [PMID: 29795770 PMCID: PMC5962263 DOI: 10.4172/2161-069x.1000266] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/30/2022]
Abstract
Phytobezoars are a rare cause of small bowel obstruction. Such cases are most commonly associated with previous abdominal surgery or poor dentition or psychiatric conditions. A 40 year old man with a virgin abdomen and excellent dentition and no underlying psychiatric condition presented with an acute abdomen. CT scan revealed a transition point between dilated proximal loops of small bowel and collapsed distal loops. Exploratory laparotomy revealed a phytobezoar unable to be milked into the cecum and an enterectomy with primary anastamosis was performed without complication. A detailed history revealing several less common predisposing factors for phytobezoars should increase clinical suspicion of a phytobezoarinduced small bowel obstruction in the setting of an acute abdomen. Vigilance in presentations of an acute abdomen improves the usefulness of medical imaging, such as a CT, to detect phytobezoars. Understanding mechanisms of phytobezoar formation helps guide management and may prevent surgery.
Collapse
Affiliation(s)
- Edward P Manning
- Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
| | | | - Masooma Niazi
- Department of Pathology, Bronx Lebanon Hospital, Bronx, NY, USA
| | - Ajay Shah
- Department of Surgery, Bronx Lebanon Hospital, Bronx, NY, USA
| |
Collapse
|
15
|
Dhakal OP, Dhakal M, Bhandari D. Phytobezoar leading to gastric outlet obstruction in a patient with diabetes. BMJ Case Rep 2014; 2014:bcr-2013-200661. [PMID: 24928925 DOI: 10.1136/bcr-2013-200661] [Citation(s) in RCA: 9] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/29/2023] Open
Abstract
Gastroparesis is a condition which results in delayed gastric emptying without gastric outflow tract obstruction. Gastrointestinal involvement in diabetes can present in various forms such as oesophageal dysmotility, gastro-oesophageal reflux disease, gastroparesis, enteropathy, non-alcoholic fatty liver disease and glycogenic hepatopathy. Gastroparesis is the most common gastric motility disorder complicating long-standing diabetes. It can sometimes lead to mechanical obstruction as a result of formation of bezoars. Phytobezoars are the most common type of bezoar and are composed of indigestible food, vegetable fibre or seeds. Poor pyloric function and decreased acid formation predisposes phytobezoars formation in patients with diabetic gastroparesis. An 80-year-old patient with diabetes in our presentation developed gastric outlet obstruction due to impaction of phytobezoar over the pylorus.
Collapse
Affiliation(s)
- Om Prakash Dhakal
- Department of Medicine, Sikkim Manipal Institute of Medical Science, Gangtok, Sikkim, India
| | - Mona Dhakal
- Department of Medicine, Sikkim Manipal Institute of Medical Science, Gangtok, Sikkim, India
| | - Dhurba Bhandari
- Department of Microbiology, Sikkim Manipal Institute of Medical Sciences and Central Referral Hospital, Gangtok, Sikkim, India
| |
Collapse
|
16
|
El Gamrani Y, Oubaha S, Gharaba S, Samlani Z, Krati K. [A bulky epigastric mass]. Rev Med Interne 2013; 35:556-7. [PMID: 24182428 DOI: 10.1016/j.revmed.2013.09.014] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/19/2013] [Revised: 09/20/2013] [Accepted: 09/30/2013] [Indexed: 11/19/2022]
Affiliation(s)
- Y El Gamrani
- Service de gastro-entérologie, CHU Mohammed VI Marrakech, Marrakech, Maroc.
| | - S Oubaha
- Laboratoire de physiologie, faculté de médecine et de pharmacie de Marrakech, Marrakech, Maroc
| | - S Gharaba
- Service de gastro-entérologie, CHU Mohammed VI Marrakech, Marrakech, Maroc
| | - Z Samlani
- Service de gastro-entérologie, CHU Mohammed VI Marrakech, Marrakech, Maroc
| | - K Krati
- Service de gastro-entérologie, CHU Mohammed VI Marrakech, Marrakech, Maroc
| |
Collapse
|
17
|
Gastric electrical stimulation for the treatment of obesity: from entrainment to bezoars-a functional review. ISRN GASTROENTEROLOGY 2013; 2013:434706. [PMID: 23476793 PMCID: PMC3582063 DOI: 10.1155/2013/434706] [Citation(s) in RCA: 8] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Download PDF] [Subscribe] [Scholar Register] [Received: 12/19/2012] [Accepted: 01/08/2013] [Indexed: 12/29/2022]
Abstract
GROWING WORLDWIDE OBESITY EPIDEMIC HAS PROMPTED THE DEVELOPMENT OF TWO MAIN TREATMENT STREAMS: (a) conservative approaches and (b) invasive techniques. However, only invasive surgical methods have delivered significant and sustainable benefits. Therefore, contemporary research exploration has focused on the development of minimally invasive gastric manipulation methods featuring a safe but reliable and long-term sustainable weight loss effect similar to the one delivered by bariatric surgeries. This antiobesity approach is based on placing external devices in the stomach ranging from electrodes for gastric electrical stimulation to temporary intraluminal bezoars for gastric volume displacement for a predetermined amount of time. The present paper examines the evolution of these techniques from invasively implantable units to completely noninvasive patient-controllable implements, from a functional, rather than from the traditional, parametric point of view. Comparative discussion over the available pilot and clinical studies related to gastric electrical stimulation outlines the promises and the fallacies of this concept as a reliable alternative anti-obesity strategy.
Collapse
|
18
|
Kim JH, Chang JH, Nam SM, Lee MJ, Maeng IH, Park JY, Im YS, Kim TH, Park IY, Han SW. Duodenal obstruction following acute pancreatitis caused by a large duodenal diverticular bezoar. World J Gastroenterol 2012; 18:5485-8. [PMID: 23082068 PMCID: PMC3471120 DOI: 10.3748/wjg.v18.i38.5485] [Citation(s) in RCA: 13] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/03/2012] [Revised: 06/21/2012] [Accepted: 06/28/2012] [Indexed: 02/06/2023] Open
Abstract
Bezoars are concretions of indigestible materials in the gastrointestinal tract. It generally develops in patients with previous gastric surgery or patients with delayed gastric emptying. Cases of periampullary duodenal divericular bezoar are rare. Clinical manifestations by a bezoar vary from no symptom to acute abdominal syndrome depending on the location of the bezoar. Biliary obstruction or acute pancreatitis caused by a bezoar has been rarely reported. Small bowel obstruction by a bezoar is also rare, but it is a complication that requires surgery. This is a case of acute pancreatitis and subsequent duodenal obstruction caused by a large duodenal bezoar migrating from a periampullary diverticulum to the duodenal lumen, which mimicked pancreatic abscess or microperforation on abdominal computerized tomography. The patient underwent surgical removal of the bezoar and recovered completely.
Collapse
|
19
|
de Toledo AP, Rodrigues FH, Rodrigues MR, Sato DT, Nonose R, Nascimento EF, Martinez CAR. Diospyrobezoar as a cause of small bowel obstruction. Case Rep Gastroenterol 2012; 6:596-603. [PMID: 23271989 PMCID: PMC3529578 DOI: 10.1159/000343161] [Citation(s) in RCA: 20] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/15/2022] Open
Abstract
Phytobezoar, a concretion of indigestible fibers derived from ingested vegetables and fruits, is the most common type of bezoar. Diospyrobezoar is a subtype of phytobezoar formed after excessive intake of persimmons (Diospyros kaki). We report the case of a diabetic man with a 5-day history of abdominal pain after massive ingestion of persimmons who developed signs of complicated small bowel obstruction. The patient had a previous history of Billroth II hemigastrectomy associated with truncal vagotomy to treat a chronic duodenal ulcer 14 years earlier. Since intestinal obstruction was suspected, he underwent emergency laparotomy that revealed an ileal obstruction with small bowel perforation and local peritonitis due to a phytobezoar that was impacted 15 cm above the ileocecal valve. After segmental intestinal resection, the patient had a good recovery and was discharged on the 6th postoperative day. This report provides evidence that diospyrobezoar should be considered as a possible cause of small bowel obstruction in patients who have previously undergone gastric surgery.
Collapse
|
20
|
Papavramidis TS, Grosomanidis V, Papakostas P, Penna S, Kotzampassi K. Intragastric balloon fundal or antral position affects weight loss and tolerability. Obes Surg 2012; 22:904-909. [PMID: 22322378 DOI: 10.1007/s11695-012-0620-5] [Citation(s) in RCA: 14] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/06/2023]
Abstract
BACKGROUND Intragastric balloons (BIB) are routinely used for weight reduction. They should be placed to the gastric fundus, as this place is believed more effective for achievement of satiety and thus weight reduction. The aim of the present study was to evaluate whether the balloon position may affect 6-month weight loss as well as first-month side-effects, i.e. nausea, vomiting, and gastroesophageal reflux. METHODS From a total of 158 BIB-treated obese individuals, 105 females were found eligible, since the balloon in the stomach was found upon removal in the same position (fundus or antrum) placed at the time of insertion. These subjects were divided into fundus and antral groups. Data related to obesity were recorded on day 0 and upon BIB removal, 6 months thereafter. Data related to transient side-effects (nausea, vomiting, gastroesophageal reflux) were recorded on days 0-3, 7, and weekly thereafter, for 1 month. RESULTS BIB placed in the antrum was found to have significantly better results on weight loss parameters, while nausea, vomiting (p = 0.02) as well as gastroesophageal reflux still remained up to the fourth week in a relation to the fundus group. Similarly, the rate of gastric distension was found significantly increased (p = 0.001) during the days 1-3 in fundus group in relation to antrum, followed by a progressive decrease in both groups. CONCLUSIONS Intragastric balloon placed in the antrum lead to better results in weight reduction but to longer duration of tolerability-related side-effects, i.e., nausea, vomiting, and gastroesophageal reflux.
Collapse
Affiliation(s)
- Theodossis S Papavramidis
- Department of Surgery, Aristotle University of Thessaloniki, 45 Agiou Dimitriou str, 54632, Thessaloniki, Greece
| | | | | | | | | |
Collapse
|
21
|
Azevedo S, Lopes J, Marques A, Mourato P, Freitas L, Lopes AI. Successful endoscopic resolution of a large gastric bezoar in a child. World J Gastrointest Endosc 2011; 3:129-32. [PMID: 21860681 PMCID: PMC3158905 DOI: 10.4253/wjge.v3.i6.129] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/20/2010] [Revised: 05/10/2011] [Accepted: 05/17/2011] [Indexed: 02/05/2023] Open
Abstract
Bezoars are masses or concretions of indigestible materials found in the gastrointestinal tract, usually in the stomach. Case reports of childhood gastric bezoars (particularly phytobezoars) are rare. In this age group they represent a therapeutic challenge, because of the combination of hard consistency and great size. The present report concerns an 8-year-old boy with a history of high fruit intake, presenting with abdominal complaints due to a large gastric phytobezoar. Successful endoscopic fragmentation coupled with suction removal was accomplished, using a standard-channel endoscope. Although laborious, it has been shown to be an efficacious and safe procedure, completed in one session. Endoscopic techniques for pediatric bezoar management may thus be cost effective, taking into account the avoidance of surgery, the length of the hospital stay and the number of endoscopic sessions.
Collapse
Affiliation(s)
- Sara Azevedo
- Sara Azevedo, Paula Mourato, Lucília Freitas, Gastrenterology Unit, Pediatric Department, University Hospital Santa Maria, Av. Professor Egas Moniz, Lisboa 1649-028, Portugal
| | | | | | | | | | | |
Collapse
|
22
|
Lee BJ, Park JJ, Chun HJ, Kim JH, Yeon JE, Jeen YT, Kim JS, Byun KS, Lee SW, Choi JH, Kim CD, Ryu HS, Bak YT. How good is cola for dissolution of gastric phytobezoars? World J Gastroenterol 2009; 15:2265-9. [PMID: 19437568 PMCID: PMC2682243 DOI: 10.3748/wjg.15.2265] [Citation(s) in RCA: 47] [Impact Index Per Article: 2.9] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/06/2023] Open
Abstract
AIM: To evaluate the efficacy of cola treatment for gastric phytobezoars, including diospyrobezoars.
METHODS: A total of 17 patients (range: 48 to 78 years) with symptomatic gastric phytobezoars treated with cola and adjuvant endoscopic therapy were reviewed. Three liters of cola lavage (10 cases) or drink (7 cases) were initially used, and then endoscopic fragmentation was done for the remnant bezoars by using a lithotripsy basket or a polypectomy snare. The overall success of dissolving a gastric phytobezoars with using three liters of cola and the clinical and endoscopic findings were compared retrospectively between four cases of complete dissolution by using only cola and 13 cases of partial dissolution with cola.
RESULTS: After 3 L of cola lavage or drinking, a complete dissolution of bezoars was achieved in four patients (23.5%), while 13 cases (76.5%) were only partially dissolved. Phytobezoars (4 of 6 cases) were observed more frequently than diospyrobezoars (0 of 11) in the group that underwent complete dissolution (P = 0.006). Gender, symptom duration, size of bezoar and method of cola administration were not significantly different between the two groups. Twelve of 13 patients with residual bezoars were completely treated with a combination of cola and endoscopic fragmentation.
CONCLUSION: The rate of complete dissolution with three liters of cola was 23.5%, but no case of diospyrobezoar was completely dissolved using this method. However, pretreatment with cola may be helpful and facilitate endoscopic fragmentation of gastric phytobezoars.
Collapse
|