Autoimmune hepatitis and eosinophilia: A rare case report

Table 1 Reported cases of autoimmune hepatitis associated with peripheral blood eosinophilia

Ref.	Panush et al[8]	Kane et al[9]	Terrier et al[10]	Omata et al[13]	Chowdry et al[3]	Farani et al[11]	Makino et al[12]	Present case
Age	14 yr old	41 yr old	16 yr old	49 yr old	18 yr old	41 yr old	7 yr old	36 yr old
Sex	Male	Female	Male	Female	Male	Male	Male	Male
Transaminases	AST 700 U/L; ALT 1560 U/L	AST 200 U/L; ALT --	AST 200 U/L; ALT 320 U/L	AST 1019 U/L; ALT 772 U/L	AST 955 U/L ALT 1194 U/L	AST 70 U/L; ALT 67 U/L	AST 419 U/L; ALT 306 U/L	AST 86 U/L; ALT 240 U/L
Eosinophil count	7.437 × 109/L	2.64 × 109/L	63.2 × 109/L	1.2 × 109/L	3.3 × 109/L	4.9 × 109/L	9 × 109/L	30 × 109/L
IgG level	2300 mg/dL	2600 mg/dL	--	1930 mg/dL	2760 mg/dL	3180 mg/dL	5234 mg/dL	3650 mg/dL
Positive antibodies	ANA, SMA	SMA	SMA	Negative	ANA, SMA	ANA	ANA	ANA, SMA
Hepatic eosinophilia	No	Yes	No	Yes	Yes	Yes	Yes	Yes
Autoimmune disease associations	Coombs positive hemolytic anemia	Ulcerative colitis, autoimmune thyroid disease	Ulcerative colitis	None	None	Arthritis	None	Crohn’s disease

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; IgG: Immunoglobulin G; ANA: Anti-nuclear antibody; SMA: Anti-smooth muscle antibody.