Retrospective Cohort Study
Copyright ©The Author(s) 2023.
World J Hepatol. Jan 27, 2023; 15(1): 68-78
Published online Jan 27, 2023. doi: 10.4254/wjh.v15.i1.68
Table 1 Baseline characteristics of patients with autoimmune hepatitis and non-chronic liver diseases patients with a positive test for severe acute respiratory syndrome coronavirus-2
VariablesBefore propensity score matching
After propensity score matching
AIH (n = 375)
Non-CLD (n = 1647915)
P value
AIH (n = 375)
Non-CLD (n = 375)
P value
Age, yr, mean ± SD53.1 ± 18.446.4 ± 18.8< 0.0153.1 ± 8.453.2 ± 8.20.97
Sex, n (%)
Female271 (72.2)893768 (54.2)< 0.01271 (72.2)256 (68.2)0.23
Ethnicity, n (%)
Hispanic or Latino37 (9.8)144535 (8.7) 0.4537 (9.8) 36 (9.6) 0.90
Race, n (%)
White238 (63.4)1028824 (62.4)0.68238 (63.4)228 (60.8)0.45
Black or African American64 (17.1)245820 (14.9)0.2464 (17.1)69 (18.4)0.63
Other65 (17.3)325638 (19.7)0.2465 (17.3)69 (18.4)0.70
Nicotine dependence, n (%)76 (20.2)181270 (10.9)< 0.0172 (19.2)74 (19.7)0.67
BMI (kg/m2), mean ± SD28.9 ± 7.0529.9 ± 7.450.0728.9 ± 7.0530.8 ± 7.650.01
Comorbidities, n (%)
Hypertension163 (43.4)384968 (23.3)< 0.01163 (43.4)159 (42.4)0.77
Ischemic heart diseases59 (15.7)119162 (7.2)< 0.0159 (15.7)57 (15.2)0.84
Heart failure38 (10.1)65245 (3.9)< 0.0138 (10.1)37 (9.8)0.90
Diabetes74 (19.7)171727 (10.4)< 0.0174 (19.7)68 (18.1)0.58
Chronic lower respiratory diseases82 (21.8)235406 (14.2)< 0.0182 (21.8)81 (21.6)0.93
Cerebrovascular diseases37 (9.8)73209 (4.4)< 0.0137 (9.8)39 (10.4)0.81
CKD of any stage46 (12.2)78265 (4.7)< 0.0146 (12.2)37 (9.8)0.29
Neoplasms125 (33.3)293362 (17.8)< 0.01125 (33.3)132 (35.2)0.59
Table 2 Baseline characteristics of patients with autoimmune hepatitis and non-autoimmune hepatitis chronic liver diseases patients with a positive test for severe acute respiratory syndrome coronavirus-2
VariablesBefore propensity score matching
After propensity score matching
AIH (n = 375)
Non-AIH CLD (n = 15790)
P value
AIH (n = 363)
Non-AIH CLD (n = 363)
P value
Age, yr, mean ± SD53.1 ± 18.560.3 ± 12.1< 0.0153.9 ± 18.154.3 ± 15.50.76
Sex, n (%)
Female267 (71.2)6517 (41.2)< 0.01262 (72.1)266 (73.2)0.74
Ethnicity, n (%)
Hispanic or Latino82 (21.8)1579 (10)< 0.0182 (22.5)67 (18.4)0.19
Race, n (%)
White236 (62.9)11132 (70.5)0.02235 (64.7)218 (60.1)0.19
Black or African American65 (17.3)2462 (15.5)0.4158 (15.9)72 (19.8)0.17
Other66 (17.6)1824 (11.5)0.0462 (17.1)61 (16.8)0.92
Nicotine dependence, n (%)87 (23.2)1831 (11.5)< 0.0189 (24.5)87 (23.9)0.94
BMI (kg/m2), mean ± SD28.9 ± 7.130.4 ± 7.480.0929 ± 7.1128.7 ± 7.790.72
Comorbidities, n (%)
Hypertension165 (44)11469 (72.6)< 0.01161 (44.3)200 (55.1)0.03
Ischemic heart diseases62 (16.5)5472 (34.6)< 0.0159 (16.2)56 (15.4)0.76
Heart failure39 (10.4)4196 (26.5)< 0.0138 (10.4)48 (13.2)0.25
Diabetes74 (19.7)7882 (49.9)0.0174 (20.4)66 (18.1)0.45
Chronic lower respiratory diseases84 (22.4)5843 (37.0)< 0.0182 (22.5)79 (21.7)0.79
Cerebrovascular diseases37 (9.8)3079 (19.4)< 0.0137 (10.1)39 (10.7)0.81
CKD of any stage49 (13.1)5102 (32.3)< 0.0146 (12.6)55 (15.1)0.33
Neoplasms131 (34.9)8400 (53.1)< 0.01124 (34.1)131 (36.1)0.59