Retrospective Study
Copyright ©The Author(s) 2022.
World J Hepatol. Apr 27, 2022; 14(4): 766-777
Published online Apr 27, 2022. doi: 10.4254/wjh.v14.i4.766
Table 1 Patient characteristics
Characteristics
SRCS without liver cirrhosis
SRCS with liver cirrhosis
P value
N = 758810 (%)N = 11920 (%)
Patient age, mean (SD)66.7 (66.6-66.8)62.7 (62.2-63.2)< 0.05
Sex< 0.05
Female293963 (39)11920 (34)
Male464847 (61)7901(66)
Race N (%)< 0.05
White546570 (72)7996 (67)
Black96975.918 (13)1676 (14)
Hispanic66092 (9)1525 (13)
Asian or Pacific Islander21930 (3)273 (2)
Native American4325 (1)118 (1)
Other22840 (3)330 (3)
Insurance, N (%)< 0.05
Medicare456880 (60)6728 (56)
Medicaid79068 (10)2495 (21)
Private188716 (25)2145 (18)
Uninsured34146 (5)552 (5)
Household median income, N (%)< 0.05
1-38999232348 (31)4271 (36)
39000-47999210114 (28)3055 (26)
48000-62900175513 (23)2595 (22)
> 63000140835 (18)1998 (17)
Bed size, N (%)< 0.05
Small124065 (16)1665 (14)
Medium230602 (30)3454 (29)
Large404218 (53)6800 (57)
Hospital region< 0.05
Northeast134309 (18)1860 (16)
Midwest170201 (22)2360 (20)
South306180 (40)4915 (41)
West148196 (20)2785 (23)
Hospital location< 0.05
Rural51220 (7)465 (4)
Urban707590 (93)11455 (96)
Charlson comorbidity index, mean (SD)< 0.05
010016 (1)0
1166938 (22)335 (3)
2176043 (23)830 (7)
3405736 (53)10755 (90)
Table 2 Propensity matched adjusted odds of decompensated liver cirrhosis markers as predictors of mortality
Markers of decompensated cirrhosis
N (%)
Adjusted odds
Lower limit
Upper limit
P value
Hypoalbuminemia460 (4)1.381.041.82< 0.05
Hepatic encephalopathy1855 (16)3.062.413.9< 0.05
Portal vein thrombosis310 (3)1.130.721.770.6
Variceal upper GI bleed825 (7)1.811.033.19< 0.05
Ascites2155 (18)1.911.622.27< 0.05
Coagulopathy 1290 (11)2.181.862.56< 0.05
SBP295 (2)2.380.698.320.17
Hepatorenal syndrome945 (8)1.691.222.34< 0.05
Table 3 Propensity matched adjusted odds of inpatient outcomes as predictors of mortality
In-hospital outcomes
Adjusted odds of mortality propensity matched- needs update
Lower limit
Upper limit
P value
Sepsis2.121.662.72< 0.05
AKI on CKD0.650.41.060.08
AKI2.722.013.68< 0.05
AKI on CKD2.241.842.74< 0.05
Cardiac arrest 4.873.856.67< 0.05
Stroke1.060.452.50.89
Any bleed/hemorrhage2.441.454.1< 0.05
Electrolyte and fluid disturbance0.950.451.990.89
All GI bleed0.420.250.73< 0.05
Respiratory failure requiring mechanical ventilation1.140.741.780.55