Nested stromal-epithelial tumour of the liver: An unusual liver entity

Figure 1 Radiological imaging. A: Abdominal magnetic resonance imaging scan showing a 16 cm diameter inhomogeneous and partially calcified (asterisk) mass of the left liver; B: Total-body ¹¹C-choline positron emission tomography showed a slight pathological uptake of the tracer in the peripheral part of the tumour (red arrows).

Figure 2 Pathological features of the reported calcifying nested stromal-epithelial tumor of the liver. A: At gross inspection the lesion shows well defined margins and is arranged in lobules; B: At histology the lesion is characterized by the presence of well defined nests of epithelial cells separated by strand of stromal cells, focally admixed with calcifying deposits (arrow); C: Scattered neoplastic cells stain positive for WT-1 immunostaining; D: Some neoplastic nuclei showed well separated green and orange probes signals (arrow), in keeping with a translocation involving EWSR1 gene (FISH); some neoplastic nuclei (asterisks) did not show the same break apart pattern.