Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Mar 18, 2017; 9(8): 427-435
Published online Mar 18, 2017. doi: 10.4254/wjh.v9.i8.427
Factors associated with long-term survival after liver transplantation: A retrospective cohort study
Sven Pischke, Marie C Lege, Moritz von Wulffen, Antonio Galante, Benjamin Otto, Malte H Wehmeyer, Uta Herden, Lutz Fischer, Björn Nashan, Ansgar W Lohse, Martina Sterneck
Sven Pischke, Marie C Lege, Moritz von Wulffen, Antonio Galante, Benjamin Otto, Malte H Wehmeyer, Ansgar W Lohse, Martina Sterneck, Department of Medicine I, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Uta Herden, Lutz Fischer, Björn Nashan, Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Author contributions: Pischke S and Lege MC contributed equally and are both first authors; this work formed part of the thesis of Lege MC; all the authors contributed equally to the study conception and design, performed the data collection, analysis and interpretation, performed the statistical analysis, and drafted and revised the manuscript.
Institutional review board statement: Not needed due to the non-clinical study design.
Informed consent statement: For this retrospective, observational study neither informed consent nor approval of the ethics committee was needed according to the Professional Code of the German Medical Association (article B.III. § 15.1) and to the recommendations of our local ethical committee (Ethikkommission der Ärztekammer Hamburg).
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Data sharing statement: No data were created and no data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Martina Sterneck, Professor, Department of Medicine I, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. sterneck@uke.de
Telephone: +49-68-06920285
Received: August 7, 2016
Peer-review started: August 8, 2016
First decision: September 28, 2016
Revised: December 2, 2016
Accepted: December 13, 2016
Article in press: December 14, 2016
Published online: March 18, 2017
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Core Tip

Core tip: Due to organ shortage and epidemiological developments, the number of older potential orthotopic liver transplant (OLT) recipients increased greatly over the last decades. In order to identify predictors for long-term survival after liver transplantation, we analysed all adult, first OLTs performed at the University Medical Center Hamburg-Eppendorf between 1997 and 1999 and compared these findings with the Eurotransplant database. Our study shows that recipient’s age and body mass index as well as hepatitis B as underlying disease are predictors of long-term survival after OLT.