Systematic Reviews
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Feb 18, 2017; 9(5): 278-287
Published online Feb 18, 2017. doi: 10.4254/wjh.v9.i5.278
Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data
Alia S Dadabhai, Behnam Saberi, Katie Lobner, Russell T Shinohara, Gerard E Mullin
Alia S Dadabhai, Behnam Saberi, Katie Lobner, Gerard E Mullin, Division of Gastroenterology and Hepatology, the Johns Hopkins University School of Medicine, Baltimore, MD 21224, United States
Russell T Shinohara, Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States
Author contributions: Dadabhai AS, Saberi B and Mullin GE contributed equally to the data evaluation, manuscript preparation, editing, figures, and final submission; Shinohara RT provided biostatistics methodology oversight, data extractions and meta-analysis with pooled data figure preparation and manuscript preparation and editing; Lobner K provided informatics methodology support, conducted the literature search, and reviewed and edited the manuscript.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
Data sharing statement: Technical appendix, statistical code, and dataset are available from the corresponding author at
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Alia S Dadabhai, MD, Assistant Professor, Division of Gastroenterology and Hepatology, the Johns Hopkins University School of Medicine, 4940 Eastern Ave A504, Baltimore, MD 21224, United States.
Telephone: +1-410-5507857 Fax: +1-410-5507861
Received: November 16, 2016
Peer-review started: November 21, 2016
First decision: December 1, 2016
Revised: December 14, 2016
Accepted: January 2, 2017
Article in press: January 3, 2017
Published online: February 18, 2017
Core Tip

Core tip: Vitamin D levels are associated with more advanced fibrosis in chronic hepatitis C.