Published online Dec 28, 2017. doi: 10.4254/wjh.v9.i36.1296
Peer-review started: October 2, 2017
First decision: November 3, 2017
Revised: November 10, 2017
Accepted: December 6, 2017
Article in press: December 7, 2017
Published online: December 28, 2017
Core tip: Hepatocellular carcinoma (HCC) is characterized by early formation of portal vein tumor thrombus (PVTT). Even after surgical removal of the tumors with PVTT in HCC patients, early recurrence has been frequently reported due to intrahepatic metastasis from PVTT. There have been reports of long-term survival after hepatectomy in patients with macroscopic PVTT. The operative mortality of major hepatectomy for HCC patients with macroscopic PVTT has not been well documented or discussed. To this end, we reviewed recent literature on the significance of hepatectomy in HCC with macroscopic PVTT with respect to the long-term survival and mortality.