Lack of hepcidin expression attenuates steatosis and causes fibrosis in the liver
Sizhao Lu, Robert G Bennett, Department of Biochemistry, University of Nebraska Medical Center, Omaha, NE 68198-5870, United States
Robert G Bennett, Division of Endocrinology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-4130, United States
Robert G Bennett, Kusum K Kharbanda, Nebraska-Western Iowa VA Health Care System, Omaha, NE 68105, United States
Kusum K Kharbanda, Duygu Dee Harrison-Findik, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-2000, United States
Author contributions: Lu S contributed to study design, data acquisition and drafting of the manuscript; Harrison-Findik DD obtained funding, contributed to study concept and supervision, and critical revision of the manuscript; Bennett RG and Kharbanda K helped with technical support and critical reading of the manuscript.
Supported by NIH grant No. R01AA017738 (to Harrison-Findik DD); and University of Nebraska Medical Center Graduate Assistantship/Fellowship (to Lu S).
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of University of Nebraska Medical Center (IACUC protocol No. 03-075-10-FC).
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Duygu Dee Harrison-Findik, DVM, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Nebraska Medical Center, 92000 UNMC, Omaha, NE 68198-2000, United States. firstname.lastname@example.org
Telephone: +1-402-5596209 Fax: +1-402-5599004
Received: August 2, 2015
Peer-review started: August 3, 2015
First decision: September 29, 2015
Revised: October 14, 2015
Accepted: November 13, 2015
Article in press: November 13, 2015
Published online: February 8, 2016