Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Nov 18, 2016; 8(32): 1384-1391
Published online Nov 18, 2016. doi: 10.4254/wjh.v8.i32.1384
Systemic-to-pulmonary artery pressure ratio as a predictor of patient outcome following liver transplantation
Annette Rebel, Dung Nguyen, Brooke Bauer, Paul A Sloan, Amy DiLorenzo, Zaki-Udin Hassan
Annette Rebel, Dung Nguyen, Brooke Bauer, Paul A Sloan, Amy DiLorenzo, Zaki-Udin Hassan, Department of Anesthesiology and Surgery, Medical Center N 202, University of Kentucky, Lexington, KY 40536, United States
Author contributions: Rebel A and Bauer B collected and analyzed the data, and drafted the manuscript; Nguyen D, Sloan PA, DiLorenzo A and Hassan ZU provided analytical oversight and supervised the study; all authors contributed and revised the manuscript for importance; all authors have read and approved the final version to be published.
Institutional review board statement: The need for informed consent of study participants was waived by the Institutional Review Board since the de-identified data review demonstrated minimal risk to patient population.
Informed consent statement: The need for informed consent of study participants was waived by the Institutional Review Board.
Conflict-of-interest statement: The authors have no conflict of interest to report.
Data sharing statement: Technical appendix, statistical code, and dataset are available from the corresponding author at arebe2@email.uky.edu.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Annette Rebel, MD, Associate Professor, Department of Anesthesiology and Surgery, Medical Center N 202, University of Kentucky, 800 Rose Street, Lexington, KY 40536, United States. arebe2@uky.edu
Telephone: +1-859-3235956 Fax: +1-859-3231080
Received: June 22, 2016
Peer-review started: June 28, 2016
First decision: September 5, 2016
Revised: September 23, 2016
Accepted: October 22, 2016
Article in press: October 24, 2016
Published online: November 18, 2016
Processing time: 141 Days and 12.5 Hours
Core Tip

Core tip: The aim of this study was to assess the value of the mean systemic-to-pulmonary artery pressure (MAP/mPAP) ratio for predicting outcomes following orthotopic liver transplant. The intraoperative pattern of this ratio has not been previously described. Performing a retrospective analysis we identified 2 different MAP/mPAP patterns: Group 1 (MAP/mPAP ratio increase during anhepatic period with postreperfusion recovery, n = 66); and Group 2 (MAP/mPAP ratio with no change during anhepatic period or decreased without recovery, n = 25). The main finding was that the lack of increased MAP/mPAP ratio in the anhepatic period was associated with longer intubation times, and prolonged hospitalization time.