Siniscalchi A, Gamberini L, Bardi T, Laici C, Gamberini E, Francorsi L, Faenza S. Role of epidural anesthesia in a fast track liver resection protocol for cirrhotic patients - results after three years of practice. World J Hepatol 2016; 8(26): 1097-1104 [PMID: 27660677 DOI: 10.4254/wjh.v8.i26.1097]
Corresponding Author of This Article
Antonio Siniscalchi, MD, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. sinianest@libero.it
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Sep 18, 2016; 8(26): 1097-1104 Published online Sep 18, 2016. doi: 10.4254/wjh.v8.i26.1097
Role of epidural anesthesia in a fast track liver resection protocol for cirrhotic patients - results after three years of practice
Antonio Siniscalchi, Lorenzo Gamberini, Tommaso Bardi, Cristiana Laici, Elisa Gamberini, Letizia Francorsi, Stefano Faenza
Antonio Siniscalchi, Lorenzo Gamberini, Tommaso Bardi, Cristiana Laici, Elisa Gamberini, Letizia Francorsi, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy
Author contributions: All the authors contributed to this manuscript.
Institutional review board statement: Approved by the Policlinico S. Orsola Malpighi review board.
Informed consent statement: Approved by the Policlinico S. Orsola Malpighi review board.
Conflict-of-interest statement: The authors of this study certify that they have no affiliations with, or involvement in any organization or entity with any financial or non-financial interest, relating to the subject matter or the materials discussed in this manuscript. This study was fully supported by the Department of Anesthesiology of the University of Bologna.
Data sharing statement: No data were created so no data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Antonio Siniscalchi, MD, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. sinianest@libero.it
Telephone: +39-05-12143440
Received: May 8, 2016 Peer-review started: May 8, 2016 First decision: June 13, 2016 Revised: June 22, 2016 Accepted: August 11, 2016 Article in press: August 15, 2016 Published online: September 18, 2016 Processing time: 129 Days and 14.9 Hours
Core Tip
Core tip: This retrospective study evaluates the potential benefits and risks of the use of epidural anaesthesia within an enhanced recovery protocol in the subpopulation of cirrhotic patients undergoing liver resection. We included all cirrhotic patients who underwent open liver resection between January 2013 and December 2015 at our Unit. The study included 126 cirrhotic patients, 86 patients received general anaesthesia and 40 combined anaesthesia. The two groups presented homogeneous characteristics. The epidural group had a lower intraoperative mean arterial pressure (P = 0.041) and received more colloid infusions (P = 0.007). Postoperative liver and kidney function did not differ significantly. Length of mechanical ventilation (P = 0.003) and hospital stay were significantly lower (P = 0.032) in the epidural group. No complications related to the epidural catheter management were recorded.
