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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 18, 2016; 8(23): 957-960
Published online Aug 18, 2016. doi: 10.4254/wjh.v8.i23.957
Published online Aug 18, 2016. doi: 10.4254/wjh.v8.i23.957
Adjuvant sorafenib in hepatocellular carcinoma: A cautionary comment of STORM trial
Jian-Hong Zhong, Bang-De Xiang, Le-Qun Li, Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Xue-Ke Du, Department of Anesthesia, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Zhong JH, Du XK and Xiang BD contributed equally to this work; Zhong JH and Du XK designed the study and wrote the manuscript; Zhong JH, Xiang BD and Li LQ analyzed the data from the included studies; all authors reviewed the manuscript and approved publication.
Supported by Guangxi Science and Technology Development Projects , No. 14124003-4 ; Guangxi University of Science and Technology Research Projects , No. KY2015LX056 ; the Self-Raised Scientific Research Fund of the Ministry of Health of Guangxi Province , Nos. Z2015621 , Z201560 1, GZZC15-34 and Z2014241 ; and the Innovation Project of Guangxi Graduate Education , No. YCBZ2015030 .
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Le-Qun Li, MD, Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, He Di Rd #71, Nanning 530021, Guangxi Zhuang Autonomous Region, China. xitongpingjia@163.com
Telephone: +86-771-5330855 Fax: +86-771-5312000
Received: April 29, 2016
Peer-review started: May 4, 2016
First decision: July 4, 2016
Revised: July 6, 2016
Accepted: July 29, 2016
Article in press: August 1, 2016
Published online: August 18, 2016
Processing time: 109 Days and 22 Hours
Peer-review started: May 4, 2016
First decision: July 4, 2016
Revised: July 6, 2016
Accepted: July 29, 2016
Article in press: August 1, 2016
Published online: August 18, 2016
Processing time: 109 Days and 22 Hours
Core Tip
Core tip: Sorafenib is effective for advanced hepatocellular carcinoma (HCC). However, its positive role as adjuvant therapy for HCC after surgery or transarterial chemoembolization is controversy.