Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Selection of patients with hepatocellular carcinoma for liver transplantation: Past and future
Arturo Soriano, Aranzazu Varona, Rajesh Gianchandani, Modesto Enrique Moneva, Javier Arranz, Antonio Gonzalez, Manuel Barrera, Liver Transplantation Unit, University Hospital Nuestra Señora de Candelaria, Santa Cruz, 38010 Santa Cruz de Tenerife, Spain
Author contributions: Soriano A and Barrera M designed the research; Varona A, Moneva ME, Arranz J and Gonzalez A performed the research; Soriano A and Gianchandani R wrote the paper; Soriano A, Varona A, Gianchandani R, Moneva ME, Arranz J, Gonzalez A and Barrera M reviewed the article and provided final approval.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Manuel Barrera, MD, Chief, Liver Transplantation Unit, University Hospital Nuestra Señora de Candelaria, Santa Cruz, Ctra del Rosario n 145, 38010 Santa Cruz de Tenerife, Spain. mbargom@yahoo.es
Telephone: +34-92-2602075 Fax: +34-92-2602075
Received: April 29, 2015
Peer-review started: May 8, 2015
First decision: October 21, 2015
Revised: November 18, 2015
Accepted: December 8, 2015
Article in press: December 11, 2015
Published online: January 8, 2016
Peer-review started: May 8, 2015
First decision: October 21, 2015
Revised: November 18, 2015
Accepted: December 8, 2015
Article in press: December 11, 2015
Published online: January 8, 2016
Core Tip
Core tip: This article aims to provide clinicians who treat patients with hepatocellular carcinoma, in whom liver transplantation may be indicated, with an actualized tool that considers a combination of morphological (size and number of tumors) and biological data (alpha fetoprotein value) and that facilitates the process of selecting candidates, predicts the indication of and response to neoadjuvant therapy prior to transplantation and also aids in the prioritization of patients once they are on the waiting list.