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World J Hepatol. May 28, 2015; 7(9): 1244-1250
Published online May 28, 2015. doi: 10.4254/wjh.v7.i9.1244
New prognostic markers in liver cirrhosis
Vincent Di Martino, Delphine Weil, Jean-Paul Cervoni, Thierry Thevenot
Vincent Di Martino, Delphine Weil, Jean-Paul Cervoni, Thierry Thevenot, Service D’hépatologie Et De Soins Intensifs Digestifs, CHU Jean Minjoz, 25000 Besançon, France
Author contributions: All authors contributed to this manuscript.
Conflict-of-interest: All authors have nothing to disclose regarding the present review.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Vincent Di Martino, Professor, Service D’hépatologie Et De Soins Intensifs Digestifs, CHU Jean Minjoz, 3 Boulevard Alexandre Fleming, 25000 Besançon, France. vdimartino@chu-besancon.fr
Telephone: +33-381-668594 Fax: +33-381-668817
Received: December 1, 2014
Peer-review started: December 2, 2014
First decision: January 8, 2015
Revised: February 2, 2015
Accepted: February 10, 2015
Article in press: February 12, 2015
Published online: May 28, 2015
Core Tip

Core tip: This review provides new insights on the prognosis of cirrhotic patients. Several biological markers account for events that strongly impact on prognosis but are not taken into account by common prognosis scores such as Child-Pugh or Model of End-stage Liver Disease. The rationale for the use of these markers is discussed on the basis of the most recent available data.