Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 8, 2015; 7(7): 993-1000
Published online May 8, 2015. doi: 10.4254/wjh.v7.i7.993
Acute kidney injury in patients with chronic liver disease
Nicolas Rognant
Nicolas Rognant, Nephrology Department, Centre Hospitalier Lyon-Sud, F69495 Pierre Benite Cedex, France
Author contributions: Rognant N solely contributed to this paper.
Conflict-of-interest: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Nicolas Rognant, MD, PhD, Nephrology Department, Centre Hospitalier Lyon-Sud, 165 Chemin du Grand Revoyet, F69495 Pierre Benite Cedex, France.
Telephone: + 33-472-678709 Fax: + 33-472-678710
Received: August 29, 2014
Peer-review started: August 29, 2014
First decision: December 17, 2014
Revised: January 5, 2015
Accepted: February 9, 2015
Article in press: February 11, 2015
Published online: May 8, 2015
Core Tip

Core tip: Acute kidney injury (AKI) is associated with detrimental effect on early survival in hospitalised cirrhotic patients. Due to several hemodynamic modifications, both at the systemic and renal level, induced by cirrhosis, these patients are at increased risk to present acute kidney injury. Recently, new diagnostic criteria have been developed to insure early detection and allow severity assessment of AKI and to optimize the patient’s treatment. The studies available so far, showed that these criteria could have a clinical interest in the management of renal dysfunction but additional data are needed to ascertain their clinical benefit.