Prospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Apr 28, 2015; 7(6): 903-909
Published online Apr 28, 2015. doi: 10.4254/wjh.v7.i6.903
Aetiological factors of Budd-Chiari syndrome in Algeria
Nawel Afredj, Nawal Guessab, Abdelbasset Nani, Sid Ahmed Faraoun, Ibtissem Ouled Cheikh, Rafik Kerbouche, Djouhar Hannoun, Zine Charef Amir, Hayet Ait Kaci, Kamel Bentabak, Aurélie Plessier, Dominique-Charles Valla, Valerie Cazals-Hatem, Marie-Hélène Denninger, Tadjeddine Boucekkine, Nabil Debzi
Nawel Afredj, Nawal Guessab, Abdelbasset Nani, Rafik Kerbouche, Tadjeddine Boucekkine, Nabil Debzi, Ibtissem Ouled Chikh, Hepatology Unit, Department of Medicine Mustapha Hospital, Algiers 16010, Algeria
Sid Ahmed Faraoun, Radiology Unit, Centre Pierre and Marie Curie, Algiers 16010, Algeria
Djouhar Hannoun, National Institute of Public Health (INSP), Algiers 16010, Algeria
Zine Charef Amir, Pathology Unit, CHU Mustapha, Algiers 16010, Algeria
Hayet Ait Kaci, Pathology Unit, Centre Pierre and Marie Curie, Algiers 16010, Algeria
Kamel Bentabak, Surgery Unit, Centre Pierre and Marie Curie, Algiers 16010, Algeria
Aurélie Plessier, Dominique-Charles Valla, Hepatology Unit, Beaujon Hospital, 75001 Paris, France
Valerie Cazals-Hatem, Pathology Unit, Beaujon Hospital, 75001 Paris, France
Marie-Hélène Denninger, Immunohematology Laboratory, Beaujon Hospital, 75001 Paris, France
Author contributions: Afredj N performed the study design, acquisition, analysis and interpretation of data, literature search, in addition of drafting the article; Guessab N, Nani A, Faraoun SA, Ouled Cheikh I, Kerbouche R, Amir ZC, Ait Kaci H, Bentabak K and Debzi N contributed to the acquisition of data and the collection of human material; Hannoun D performed the statistical analysis of data; Plessier A, Cazals-Hatem V and Denninger MH contributed to the research; Boucekkine T, Valla DC and Debzi N contributed to final revising of the article and providing financial support for this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nawel Afredj, MD, Associate professor, Hepatology Unit, Department of Medicine, Mustapha Hospital, Place du 1 Mai DZ-Algiers, Algiers 16010, Algeria. afnawel@yahoo.fr
Telephone: +213-21-235555 Fax: +213-21-235243
Received: July 26, 2014
Peer-review started: July 27, 2014
First decision: August 14, 2014
Revised: August 29, 2014
Accepted: March 4, 2015
Article in press: March 5, 2015
Published online: April 28, 2015
Core Tip

Core tip: Budd-Chiari syndrome (BCS) is a rare disease, but it seems quite common in our country and in North Africa in general. However, we do not know the etiological features of this disease in our region. We collected 115 cases of BCS in 6 years. A fairly complete etiologic assessment was achieved. We identified the cause of BCS in 77%. It was multifactorial in 27%. The etiologies were dominated by the myeloproliferative disease 34%, followed by antiphospholipid syndrome in 21%. Finally, the etiological distribution in our patients does not differ too much from what is reported in Western countries.