Shrestha SM. Liver cirrhosis in hepatic vena cava syndrome (or membranous obstruction of inferior vena cava). World J Hepatol 2015; 7(6): 874-884 [PMID: 25937864 DOI: 10.4254/wjh.v7.i6.874]
Corresponding Author of This Article
Santosh Man Shrestha, MBBS, DTM&H, MRCP, FRCPE, Liver Foundation Nepal, Sitapaela Height, Ward No 2, Kathmandu, Nepal. smshrestha1938@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Apr 28, 2015; 7(6): 874-884 Published online Apr 28, 2015. doi: 10.4254/wjh.v7.i6.874
Liver cirrhosis in hepatic vena cava syndrome (or membranous obstruction of inferior vena cava)
Santosh Man Shrestha
Santosh Man Shrestha, Liver Foundation Nepal, Sitapaela Height, Kathmandu, Nepal
Author contributions: The author solely contributed to this work.
Conflict-of-interest: The author has no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Santosh Man Shrestha, MBBS, DTM&H, MRCP, FRCPE, Liver Foundation Nepal, Sitapaela Height, Ward No 2, Kathmandu, Nepal. smshrestha1938@gmail.com
Telephone: +977-1-4033275
Received: July 4, 2014 Peer-review started: July 11, 2014 First decision: August 28, 2014 Revised: December 30, 2014 Accepted: January 15, 2015 Article in press: January 19, 2015 Published online: April 28, 2015
Core Tip
Core tip: Previously considered congenital and diagnosed late hepatic vena cava syndrome (HVCS) is a dynamic life-long disease related to bacterial infection that begins insidiously often in childhood and leads to development of cirrhosis and hepatocellular carcinoma. Localized stenosis, the sequel of the initial lesion persists life-long makes it vulnerable to subsequent bacterial infection which is followed by thrombosis in inferior vena cava (IVC) and intra-hepatic veins resulting in recurrent ischemic liver damage. As it frequently occurs as a co-morbid condition in patients with chronic hepatitis B or C infection or alcohol use, patients with cirrhosis in developing countries should be assessed for presence of HVCS by ultrasonography of IVC.
