Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Nov 8, 2015; 7(25): 2603-2609
Published online Nov 8, 2015. doi: 10.4254/wjh.v7.i25.2603
Hepatocellular adenoma: An update
Adarsh Vijay, Ahmed Elaffandi, Hatem Khalaf
Adarsh Vijay, Hatem Khalaf, Hamad Medical Corporation, Doha 3050, Qatar
Ahmed Elaffandi, National Cancer Institute, Cairo University, Cairo 3665, Egypt
Author contributions: Vijay A and Elaffandi A designed the paper and wrote the review article; Khalaf H revised the paper.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Ahmed Elaffandi, MD, FRCS, Senior Lecturer, National Cancer Institute, Cairo University, Cairo University Rd, Cairo 3665, Egypt.
Telephone: +974-33-578294
Received: May 11, 2015
Peer-review started: May 12, 2015
First decision: July 25, 2015
Revised: September 30, 2015
Accepted: October 23, 2015
Article in press: October 27, 2015
Published online: November 8, 2015
Core Tip

Core tip: Hepatocellular adenomas despite being benign liver neoplasms often pose diagnostic and therapeutic challenges. Studies at the molecular level have provided new insights into the genetics and pathophysiology of these lesions. These in turn have raised questions over their existing management modalities. This article provides a comprehensive review and update on the topic.