Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Feb 27, 2015; 7(2): 261-269
Published online Feb 27, 2015. doi: 10.4254/wjh.v7.i2.261
Role of surgical resection for hepatocellular carcinoma based on Japanese clinical guidelines for hepatocellular carcinoma
Hisashi Nakayama, Tadatoshi Takayama
Hisashi Nakayama, Tadatoshi Takayama, Department of Digestive Surgery, Nihon University School of Medicine, Itabashi-ku, Tokyo 173-8610, Japan
Author contributions: Both authors contributed to this work.
Supported by A Grant-in-Aid for Scientific Research (C) 25350856 from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Hisashi Nakayama, MD, PhD, Department of Digestive Surgery, Nihon University School of Medicine, 30-1, Oyaguchikami-machi, Itabashi-ku, Tokyo 173-8610, Japan.
Telephone: +81-3-35542345 Fax: +81-3-39578299
Received: August 27, 2014
Peer-review started: August 28, 2014
First decision: September 16, 2014
Revised: November 3, 2014
Accepted: November 17, 2014
Article in press: November 19, 2014
Published online: February 27, 2015
Core Tip

Core tip: In the Algorithm for Diagnosis and Treatment in the Japanese Evidence-Based Clinical Practice Guidelines for Hepatocellular Carcinoma, the treatment strategy is determined by three major factors: liver function and the number and size of tumors. The algorithm is quite simple, consisting of fewer components than the Barcelona-Clinic Liver Cancer staging system. In this article, we describe the roles of the treatment algorithm in hepatectomy and perioperative management of hepatocellular carcinoma.