Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jul 8, 2015; 7(13): 1735-1741
Published online Jul 8, 2015. doi: 10.4254/wjh.v7.i13.1735
Pancreaticobiliary reflux as a high-risk factor for biliary malignancy: Clinical features and diagnostic advancements
Reiji Sugita
Reiji Sugita, Department of Radiology, Sendai City Medical Center, Sendai, Miyagi 983-8520, Japan
Author contributions: Sugita R solely contributed to this paper.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Reiji Sugita, MD, Department of Radiology, Sendai City Medical Center, 5-22-1, Tsurugaya, Miyagino-ku, Sendai, Miyagi 983-8520, Japan. rsugita@openhp.or.jp
Telephone: +81-22-2521111 Fax: +81-22-2529431
Received: January 27, 2015
Peer-review started: January 28, 2015
First decision: March 6, 2015
Revised: March 18, 2015
Accepted: April 16, 2015
Article in press: April 20, 2015
Published online: July 8, 2015
Core Tip

Core tip: Pancreaticobiliary reflux (PBR) is an important pathologic state that can cause biliary malignancy. PBR can occur regardless of whether the patient has pancreaticobiliary maljunction (PBM) or not. Although it has long been possible to diagnose PBM by various imaging modalities, PBR without PBM has remained difficult to assess. Therefore, the pathological features of PBR without PBM have not been yet fully elucidated. Lately, a new method of diagnosing PBR without PBM has appeared, and the features of PBR without PBM should soon be better understood.