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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jun 28, 2015; 7(12): 1617-1631
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1617
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1617
Predictive factors associated with hepatitis C antiviral therapy response
Lourianne Nascimento Cavalcante, André Castro Lyra, Hospital Sao Rafael - Gastro-Hepatology Service, Salvador, Bahia 41253-190, Brazil
André Castro Lyra, Department of Medicine, Federal University of Bahia, Salvador, Bahia 40026-010, Brazil
Author contributions: Cavalcante LN and Lyra AC contributed equally to this work.
Conflict-of-interest: The authors have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lourianne Nascimento Cavalcante, MD, Hospital Sao Rafael - Gastro-Hepatology Service, Diretoria Científica, 6° andar Sao Rafael Av. 2152 - Sao Marcos, Salvador, Bahia 41253-190, Brazil. lourianne@gmail.com
Telephone: +55-71-32816432 Fax: +55-71-32816855
Received: August 28, 2014
Peer-review started: August 29, 2014
First decision: November 14, 2014
Revised: December 16, 2014
Accepted: May 5, 2015
Article in press: May 6, 2015
Published online: June 28, 2015
Processing time: 304 Days and 22.2 Hours
Peer-review started: August 29, 2014
First decision: November 14, 2014
Revised: December 16, 2014
Accepted: May 5, 2015
Article in press: May 6, 2015
Published online: June 28, 2015
Processing time: 304 Days and 22.2 Hours
Core Tip
Core tip: Treatment of chronic hepatitis C has been changing very rapidly in recent years. The chances of cure have increased with the new drugs. Predictive factors of sustained treatment response in the “age” of based-interferon therapy is becoming less important with the arrival of the direct acting antivirals, however, viral genotype, cirrhosis and viral kinetics may still impact on therapy outcome with the new available drugs.