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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Hepatitis C and kidney disease: An overview and approach to management
Ahmad Najib Azmi, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Kuala Lumpur 55100, Malaysia
Soek-Siam Tan, Department of Hepatology, Selayang Hospital, Selangor 68100, Malaysia
Rosmawati Mohamed, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
Author contributions: Azmi AN, Tan SS and Mohamed R equally contributed to the present work; Azmi AN drafted, wrote, edited and revised the article; Tan SS and Mohamed R equally contributed to revising, editing and writing the article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ahmad Najib Azmi, MBBS, MMed, Senior Lecturer, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, 13th Floor, Menara B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia. najibaz@usim.edu.my
Telephone: +60-3-42892400 Fax: +60-3-42892477
Received: September 4, 2014
Peer-review started: September 5, 2014
First decision: September 28, 2014
Revised: October 13, 2014
Accepted: November 7, 2014
Article in press: November 10, 2014
Published online: January 27, 2015
Processing time: 128 Days and 2.9 Hours
Peer-review started: September 5, 2014
First decision: September 28, 2014
Revised: October 13, 2014
Accepted: November 7, 2014
Article in press: November 10, 2014
Published online: January 27, 2015
Processing time: 128 Days and 2.9 Hours
Core Tip
Core tip: There is a strong association between hepatitis C virus (HCV) infection and chronic kidney disease with negative impact on survival in hemodialysis and post renal transplant HCV infected patients. Recent data showed that treatment of HCV improves outcomes. In HCV infected diabetics, effective anti-HCV treatment reduces the incidence of end stage renal disease. There are now major advances in HCV treatment which may dramatically change the treatment approach in hepatitis C infected patients.