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World J Hepatol. Jul 27, 2014; 6(7): 532-537
Published online Jul 27, 2014. doi: 10.4254/wjh.v6.i7.532
Published online Jul 27, 2014. doi: 10.4254/wjh.v6.i7.532
Portal vein thrombosis with protein C-S deficiency in a non-cirrhotic patient
Gustavo A Rodríguez-Leal, Segundo Morán, Laboratory of Gastrohepatology Research, Hospital de Pediatría, CMN Siglo XXI, Mexican Institute of Social Security, Delegación Cuauhtémoc, CP 06720, México
Gustavo A Rodríguez-Leal, Gastroenterology Department, Médica Sur Clinic and Foundation, Ciudad de México, DF 14050, México
Roberto Corona-Cedillo, Rocío Brom-Valladares, Radiology Department, Médica Sur Clinic and Foundation, Ciudad de México, DF 14050, México
Author contributions: Rodríguez-Leal GA drafted the manuscript, provided patient details and made the suggested revisions; Morán S assisted in drafting the manuscript, reviewed the manuscript and made suggestions on revisions, and assisted with journal submission; Corona-Cedillo R and Brom-Valladares R reviewed the manuscript and made suggestions on revisions, and provided the radiologic material and comments.
Correspondence to: Segundo Morán, MD, Laboratory of Gastrohepatology Research, Hospital de Pediatría, CMN Siglo XXI, Mexican Institute of Social Security, Av Cuauhtémoc 330, Colonia Doctores, Delegación Cuauhtémoc, CP 06720, México. segundomoran@hotmail.com
Telephone: +52-55-56276900 Fax: +52-55-57610952
Received: December 4, 2013
Revised: March 11, 2014
Accepted: May 28, 2014
Published online: July 27, 2014
Processing time: 233 Days and 9.5 Hours
Revised: March 11, 2014
Accepted: May 28, 2014
Published online: July 27, 2014
Processing time: 233 Days and 9.5 Hours
Core Tip
Core tip: Abdominal pain, diarrhea, rectal bleeding, abdominal distention, ascites, anorexia, fever, lactacidosis, sepsis, and splenomegaly are common features of acute portal vein thrombosis (PVT). Etiological factors in non-cirrhotic PVT patients are prothrombotic states and local factors, although more than one factor is often identified. Our patient, a 63-year-old man, without personal or familial history of venous thromboembolism developed portal and mesenteric vein thrombosis after an acute gastrointestinal infection by Escherichia coli. Clinicians need to be aware of this potential complication in patients with persistent abdominal pain and ascites after abdominal infections.