Published online Jun 27, 2014. doi: 10.4254/wjh.v6.i6.363
Revised: February 7, 2014
Accepted: April 11, 2014
Published online: June 27, 2014
Core tip: The significance of primary prevention of bleeding from esophageal varices in patients with liver cirrhosis is major, considering the high mortality rates that accompany the acute bleeding episode. Current management guidelines suggest the use of either non-selective beta-blockers or endoscopic band ligation with same efficacy between them. In this review, we summarize data from randomized clinical trials or prospective studies together with meta-analytical data, when applicable, to present the most updated recommendations on primary prevention of esophageal variceal bleeding.