Kinjo N, Kawanaka H, Akahoshi T, Matsumoto Y, Kamori M, Nagao Y, Hashimoto N, Uehara H, Tomikawa M, Shirabe K, Maehara Y. Portal vein thrombosis in liver cirrhosis. World J Hepatol 2014; 6(2): 64-71 [PMID: 24575165 DOI: 10.4254/wjh.v6.i2.64]
Corresponding Author of This Article
Nao Kinjo, MD, Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. email@example.com
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nao Kinjo, Hirofumi Kawanaka, Tomohiko Akahoshi, Yoshihiro Matsumoto, Masahiro Kamori, Yoshihiro Nagao, Naotaka Hashimoto, Hideo Uehara, Morimasa Tomikawa, Ken Shirabe, Yoshihiko Maehara, Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
Nao Kinjo, Department of Gastroenterological Surgery, National Kyushu Cancer Center, Fukuoka 811-1395, Japan
Author contributions: Kinjo N drafted the article; Matsumoto Y, Kamori M, Nagao Y, Hashimoto N and Uehara H contributed to the collection and assembly of manuscripts; Kawanaka H, Akahoshi T, Tomikawa M and Shirabe K participated in the critical revision of the article for important intellectual content; Maehara Y contributed to the final approval of the article.
Correspondence to: Nao Kinjo, MD, Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. firstname.lastname@example.org
Telephone: +81-92-6425466 Fax: +81-92-6425482
Received: November 11, 2013 Revised: December 22, 2013 Accepted: January 13, 2014 Published online: February 27, 2014
Core tip: Portal vein thrombosis (PVT) is considered to be a frequent complication of liver cirrhosis; however, very few data are available on the natural history and management of PVT in cirrhosis, despite its association with potentially life-threatening conditions. The understanding and information on the management of PVT in cirrhosis are incomplete. The aims of this review are to: (1) assemble data on the physiopathological mechanism, clinical findings, diagnosis and management of PVT in cirrhosis; (2) describe the principal factors most frequently involved in PVT development; and (3) summarize the recent knowledge concerning diagnostic and therapeutic procedures.