Systematic Review
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World J Hepatol. Jan 27, 2014; 6(1): 55-63
Published online Jan 27, 2014. doi: 10.4254/wjh.v6.i1.55
Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review
Archita Sood, Mariana Castrejón, Sammy Saab
Archita Sood, Department of Medicine, Olive View Medical Center, Sylmar, CA 91342, United States
Mariana Castrejón, Department of Surgery, University of California at Los Angeles Medical Center, Los Angeles, CA 90095, United States
Sammy Saab, Departments of Medicine and Surgery, University of California at Los Angeles Medical Center, Los Angeles, CA 90095, United States
Author contributions: Saab S designed research; Saab S and Sood A performed research; Saab S, Castrejón M and Sood A analyzed data; Saab S and Sood A wrote the paper.
Correspondence to: Sammy Saab, MD, MPH, AGAF, Departments of Medicine and Surgery, University of California at Los Angeles Medical Center, 200 Medical Plaza, Suite 214, Los Angeles, CA 90095, United States. ssaab@mednet.ucla.edu
Telephone: +1-310-2066705 Fax: +1-310-2064197
Received: July 14, 2013
Revised: October 16, 2013
Accepted: December 12, 2013
Published online: January 27, 2014
Processing time: 195 Days and 23.6 Hours
Core Tip

Core tip: Liver complications in patients with human immunodeficiency virus (HIV) is emerging as a public health concern. The appropriate management of HIV-infected persons with suspected nodular regenerative hyperplasia (NRH) is yet to be outlined. However, NRH is a clinically subtle condition that is difficult to diagnose, and it is important to be able to manage it according to the best available evidence. We believe the implications of our manuscript will have immediate clinical implications.