Case Report
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World J Hepatol. May 27, 2013; 5(5): 296-297
Published online May 27, 2013. doi: 10.4254/wjh.v5.i5.296
Gram-negative bacteria causing infective endocarditis: Rare cardiac complication after liver transplantation
Susan George, Joy Varghese, Sujatha Chandrasekhar, Rajasekar Perumalla, Mettu Srinivas Reddy, Venkataraman Jayanthi, Mohamed Rela
Susan George, Department of Cardiology, Global Hospitals and Health City, Chennai 600100, India
Joy Varghese, Venkataraman Jayanthi, Mohamed Rela, Department of Hepatology and Liver Transplantation, Global Hospitals and Health City, Chennai 600100, India
Sujatha Chandrasekhar, Department of Microbiology, Global Hospitals and Health City, Chennai 600100, India
Rajasekar Perumalla, Mettu Srinivas Reddy, Mohamed Rela, Institute of HPB and Transplantation, Global Hospitals and Health City, Chennai 600100, India
Author contributions: George S was the cardiologist taking care of the patient; Varghese J worked up the case and drafted the initial manuscript; Chandrasekar S was the microbiologist who did the culture and isolated the organism; Perumalla R and Reddy MS surgeons involved in the liver transplant; Jayanthi V worked up the case and edited the manuscript; Rela M was liver transplant surgeon heading the liver surgery and transplant team.
Correspondence to: Dr. Joy Varghese, Department of Hepatology and Liver Transplantation, Global Hospitals and Health City, 439, Cheran Nagar, Sholinganallur-Medavakkam Road, Perumbakkam, Chennai 600100, Tamil Nadu, India. joyvargese@gmail.com
Telephone: +91-44-22777000 Fax: +91-44-22777100
Received: March 6, 2013
Revised: May 3, 2013
Accepted: May 7, 2013
Published online: May 27, 2013
Core Tip

Core tip: A pre-transplant cardiac assessment should include a careful evaluation for underlying valvular pathology. Bacterial endocarditis can however still occur in liver transplant recipients with normal cardiac valves. Gram negative bacteria though rare can be a causative agent for infective endocarditis. High index of suspicion for bacterial endocarditis is essential when investigating transplant recipients for fever of uncertain origin.