Published online May 27, 2013. doi: 10.4254/wjh.v5.i5.281
Revised: April 30, 2013
Accepted: May 8, 2013
Published online: May 27, 2013
Core tip: We have designed this study to explore the prevalence of and risk factors for nonalcoholic steatohepatitis (NASH) in nonalcoholic fatty liver disease patients. Other causes of liver disease were excluded. A total of 493 patients with sonographic evidence of fatty change were considered, and 177 of these patients were evaluated and confirmed by liver biopsy after making exclusions. Females were predominant (250, 57.0%). Central obesity was more prevalent among the patients compared with overall obesity. NASH was observed in 75 (42.4%) of the cases. The presence of diabetes and elevated gamma-glutamyl transpeptidase could differentiate NASH from simple steatosis. Serum alanine aminotransferase and aspartate aminotransferase could not be used to detect NASH.