Original Article
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Hepatol. Apr 27, 2013; 5(4): 170-181
Published online Apr 27, 2013. doi: 10.4254/wjh.v5.i4.170
Hypothermia predicts hepatic failure after extensive hepatectomy in mice
Norifumi Ohashi, Tomohide Hori, Shinji Uemoto, Sura Jermanus, Feng Chen, Akimasa Nakao, Justin H Nguyen
Norifumi Ohashi, Akimasa Nakao, Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
Tomohide Hori, Shinji Uemoto, Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
Sura Jermanus, Feng Chen, Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, United States
Justin H Nguyen, Division of Transplant Surgery, Department of Transplantation, Mayo Clinic, Jacksonville, FL 32224, United States
Author contributions: Nguyen JH designed this study; Ohashi N performed the surgery, the assays and statistical analysis, and wrote the initial draft; Hori T performed the additional surgery for the second assays to confirm the initial results; Jermanus S and Chen F assisted with the assays; Hori T and Nguyen JH contributed to further drafts; Uemto S and Nakao A provided important advice for this research; Nguyen JH supervised this research.
Supported by NIH DK064361, NIH R01NS051646 and the Deason Foundation, to Nguyen JH; the Uehara Memorial Foundation, No. 200940051, to Hori T
Correspondence to: Tomohide Hori, MD, PhD, Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoinkawara-cho, Sakyo-ku, Kyoto 606-8507, Japan. horit@kuhp.kyoto-u.ac.jp
Telephone: +81-75-7513111 Fax: +81-75-7513106
Received: February 20, 2012
Revised: November 24, 2012
Accepted: December 22, 2012
Published online: April 27, 2013
Core Tip