Published online Dec 27, 2013. doi: 10.4254/wjh.v5.i12.696
Revised: November 5, 2013
Accepted: November 18, 2013
Published online: December 27, 2013
Core tip: A 68-year-old man with hepatitis C virus-related cirrhosis was admitted to our Unit for a diagnostic evaluation of three focal liver lesions detected by regular surveillance ultrasound. Computer tomography scans of abdomen allowed a diagnosis of single nodule hepatocellular carcinoma (HCC) and showed two centimetric liver nodules suspected for metastases and a luminal narrowing with thickening of the colon. The subsequent colonoscopy and ultrasound-guided biopsy of the three focal liver lesions confirmed a diagnosis of colorectal cancer with liver metastases together with a single nodule HCC. Our experience highlights the potential coexistence of two different neoplasms in a cirrhotic liver and the complexity in the proper diagnosis and management of the two tumours.