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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Hepatol. Nov 27, 2013; 5(11): 603-611
Published online Nov 27, 2013. doi: 10.4254/wjh.v5.i11.603
Published online Nov 27, 2013. doi: 10.4254/wjh.v5.i11.603
Matching donor to recipient in liver transplantation: Relevance in clinical practice
Mettu Srinivas Reddy, Mohamed Rela, Institute of Liver Diseases and Transplantation, Global Hospital and Health City, Chennai 600100, India
Joy Varghese, Jayanthi Venkataraman, Department of Hepatology and Transplantation, Institute of Liver Diseases and Transplantation, Global Hospital and Health City, Chennai 600100, India
Author contributions: All authors contributed to the manuscript.
Correspondence to: Mettu Srinivas Reddy, PhD, Institute of Liver Diseases and Transplantation, Global Hospital and Health City, 439 Cheran Nagar Perumbakkam, Chennai 600100, India. smettu.reddy@gmail.com
Telephone: +91-44-2777000 Fax: +91-44-2777100
Received: October 15, 2013
Revised: October 23, 2013
Accepted: November 2, 2013
Published online: November 27, 2013
Revised: October 23, 2013
Accepted: November 2, 2013
Published online: November 27, 2013
Core Tip
Core tip: Multiple donor and recipient factors impact graft survival after liver transplantation. In addition, interaction between donor, graft and recipient factors may significantly affect management and outcomes. Appropriate matching based on donor-organ-recipient variables can avoid wastage of liver grafts, improve outcomes and decrease graft loss. Modification of surgical techniques and innovative peri-transplant strategies can expand the donor pool by utilizing grafts from marginal donors that are traditionally turned down.