Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 27, 2025; 17(8): 108333
Published online Aug 27, 2025. doi: 10.4254/wjh.v17.i8.108333
Risk factors and predictive modeling of early postoperative liver function abnormalities
Lin Zhong, Hao-Yuan Wang, Xiao-Na Li, Qiong Ling, Ning Hao, Xiang-Yu Li, Gao-Feng Zhao, Min Liao
Lin Zhong, Hao-Yuan Wang, Qiong Ling, Min Liao, Second Clinical Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Xiao-Na Li, Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Ning Hao, Xiang-Yu Li, Gao-Feng Zhao, Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Co-corresponding authors: Gao-Feng Zhao and Min Liao.
Author contributions: Zhong L and Liao M contributed to the conceptualization; Zhong L and Zhao GF were responsible for writing the original draft; Wang H-Y and Li X-N jointly conducted the formal analysis; Ling Q, Li XY, and Hao N collaborated on writing, reviewing, and editing; and all authors have read and approve the final manuscript.
Supported by Guangdong Provincial Hospital of Chinese Medicine Science and Technology Research Special Project, No. YN2023WSSQ01; and State Key Laboratory of Traditional Chinese Medicine Syndrome.
Institutional review board statement: This study was approved by the Provincial Hospital of Chinese Medicine on February 2, 2024 (approval number: YE2024-041-01).
Informed consent statement: The ethics committee waived the informed consent forms of all patients.
Conflict-of-interest statement: All authors declare that they have no competing financial interests or personal relationships that may have influenced the work reported in this study.
Data sharing statement: The datasets used and analyzed in the current study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Liao, Second Clinical Hospital of Guangzhou University of Chinese Medicine, No. 111 Dade Road, Guangzhou 510120, Guangdong Province, China. liaomin23@aliyun.com
Received: April 13, 2025
Revised: May 28, 2025
Accepted: July 21, 2025
Published online: August 27, 2025
Processing time: 137 Days and 5.3 Hours
Core Tip

Core Tip: Elevated preoperative liver enzymes, thrombocytopenia, prolonged anesthesia and sevoflurane use are important risk factors for postoperative liver function abnormalities, and the prediction model constructed on the basis of these variables predicted well.