Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Apr 27, 2025; 17(4): 105065
Published online Apr 27, 2025. doi: 10.4254/wjh.v17.i4.105065
Correlation of liver imaging and transient elastography among patients with hepatitis C at a safety net hospital
Hima Veeramachaneni, Bobak Moazzami, Navila Sharif, Emad Qayed, Lesley S Miller
Hima Veeramachaneni, Division of Transplant Surgery and Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States
Bobak Moazzami, Division of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States
Navila Sharif, J Willis Hurst Internal Medicine Residency Program, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States
Emad Qayed, Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, United States
Lesley S Miller, Division of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, United States
Author contributions: Veeramachaneni H, Qayed E, and Miller LS designed the study; Veeramachaneni H, Moazzami B, Sharif N, and Qayed E, and Miller LS analyzed the data and wrote the manuscript; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Emory University, approval No. STUDY00001504.
Informed consent statement: Our study received an institutional review board statement waiver for informed consent and was a retrospective study with de-identified information so we do not have a signed informed consent document.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Our study received an institutional review board statement waiver for informed consent, but the presented data are anonymized, and the risk of identification is low.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lesley S Miller, MD, FACP, Professor, Division of General Internal Medicine, Department of Medicine, Emory University School of Medicine, 49 Jesse Hill Jr Dr SE, Atlanta, GA 30303, United States. lmille2@emory.edu
Received: January 10, 2025
Revised: March 3, 2025
Accepted: April 8, 2025
Published online: April 27, 2025
Processing time: 105 Days and 3.8 Hours
Core Tip

Core Tip: Conventional liver imaging and transient elastography (TE) are commonly used to assess liver fibrosis and steatosis in individuals with hepatitis C virus. This study evaluates the diagnostic performance of imaging findings in detecting fibrosis and steatosis across different disease stages and their correlation with TE measurements. While imaging demonstrates high specificity for advanced liver disease, its limited sensitivity in earlier disease stages underscores the need for a multimodal approach. These findings help inform clinicians in resource-limited settings on the strengths and limitations of liver imaging when TE is unavailable.