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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Feb 27, 2025; 17(2): 102152
Published online Feb 27, 2025. doi: 10.4254/wjh.v17.i2.102152
Published online Feb 27, 2025. doi: 10.4254/wjh.v17.i2.102152
Predictors and prognosticators of outcomes in alcoholic hepatitis: A retrospective single center study
Kevin Yang, Naren Nallapeta, Nariman Hossein-Javaheri, Alexander Carlson, Brian Quigley, Thomas Mahl, Department of Gastroenterology and Hepatology, University at Buffalo, Buffalo, NY 14203, United States
Author contributions: Yang K, Nallapeta N, Hossein-Javaheri N, and Carlson A wrote and edited the article and reviewed the literature; Quigley B contributed the statistical analysis; Mahl T edited the article and is the article guarantor.
Institutional review board statement: The study was reviewed and approved by the University at Buffalo Institutional Review Board (No. STUDY00006976).
Informed consent statement: Consent was not obtained but the presented data are anonymized and risk of identification is low.
Conflict-of-interest statement: There are no conflicts of interest to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at huaxing159357@gmail.com. No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kevin Yang, MD, Physician, Department of Gastroenterology and Hepatology, University at Buffalo, 955 Main St, Buffalo, NY 14203, United States. huaxing159357@gmail.com
Received: October 10, 2024
Revised: November 23, 2024
Accepted: January 15, 2025
Published online: February 27, 2025
Processing time: 133 Days and 4.6 Hours
Revised: November 23, 2024
Accepted: January 15, 2025
Published online: February 27, 2025
Processing time: 133 Days and 4.6 Hours
Core Tip
Core Tip: Our manuscript evaluates the utility of pre-day 7 Lille scores. Calculating the Lille score as early as day 3 can determine the need for glucocorticoids in patients with severe alcoholic hepatitis and potentially limit the side effects of unnecessary steroid therapy. Day 3-7 Lille scores all show comparable efficacy in predicting response to steroids and mortality.