Liu XC, Yan HH, Wei W, Du Q. Idiopathic portal hypertension misdiagnosed as hepatitis B cirrhosis: A case report and review of the literature. World J Hepatol 2025; 17(2): 100923 [DOI: 10.4254/wjh.v17.i2.100923]
Corresponding Author of This Article
Qin Du, Chief Physician, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. duqin@zju.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Feb 27, 2025; 17(2): 100923 Published online Feb 27, 2025. doi: 10.4254/wjh.v17.i2.100923
Idiopathic portal hypertension misdiagnosed as hepatitis B cirrhosis: A case report and review of the literature
Xiao-Chen Liu, Hui-Hui Yan, Wei Wei, Qin Du
Xiao-Chen Liu, Hui-Hui Yan, Wei Wei, Qin Du, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Co-corresponding authors: Wei Wei and Qin Du.
Author contributions: Liu XC and Yan HH contributed to manuscript writing and editing, and data collection; Wei W and Du Q contributed to conceptualization and supervision, both authors contributed equally to this article, and are co-first authors of this manuscript; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qin Du, Chief Physician, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. duqin@zju.edu.cn
Received: August 30, 2024 Revised: January 10, 2025 Accepted: January 23, 2025 Published online: February 27, 2025 Processing time: 173 Days and 19.6 Hours
Core Tip
Core Tip: Idiopathic portal hypertension (IPH) is challenging to diagnose due to its rarity and non-specific clinical presentation. This report describes the case of a 69-year-old female with recurrent hematemesis, initially misdiagnosed with viral hepatitis B cirrhosis. Subsequent evaluation revealed IPH with esophageal and gastric varices. The diagnostic challenge was compounded by the absence of specific biomarkers and imaging findings, making liver biopsy essential. Treatment primarily involves symptomatic management and endoscopic intervention. The patient demonstrated significant improvement following treatment, highlighting the importance of accurate diagnosis and tailored management. This case underscores the complexities of diagnosing and managing IPH, emphasizing the need for further research to improve diagnostic accuracy and treatment efficacy in this rare disorder.
