Review
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Sep 27, 2024; 16(9): 1229-1246
Published online Sep 27, 2024. doi: 10.4254/wjh.v16.i9.1229
Hematological abnormalities in liver cirrhosis
Oscar Manuel Fierro-Angulo, José Alberto González-Regueiro, Ariana Pereira-García, Astrid Ruiz-Margáin, Fernando Solis-Huerta, Ricardo Ulises Macías-Rodríguez
Oscar Manuel Fierro-Angulo, José Alberto González-Regueiro, Ariana Pereira-García, Astrid Ruiz-Margáin, Ricardo Ulises Macías-Rodríguez, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico 14080, Mexico
Fernando Solis-Huerta, Department of Hematology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico 14080, Mexico
Co-first authors: Oscar Manuel Fierro-Angulo and José Alberto González-Regueiro.
Author contributions: Fierro-Angulo OM and González-Regueiro JA contributed to conception and design of the review, they are co-first authors of this manuscript; Fierro-Angulo OM, González-Regueiro JA, Pereira-García A, Ruiz-Margáin A, Solis-Huerta F, and Macías-Rodríguez RU contributed to literature review, writing and analysis of data, drafting and critical revision; Ruiz-Margáin A and Macías-Rodríguez RU contributed to supervision, editing of the content of the manuscript and writing the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ricardo Ulises Macías-Rodríguez, MD, MSc, PhD, Assistant Professor, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Col. Belisario Domínguez Sección XVI, Mexico 14080, Mexico. ricardomacro@yahoo.com.mx
Received: June 6, 2024
Revised: August 9, 2024
Accepted: August 22, 2024
Published online: September 27, 2024
Processing time: 109 Days and 5.5 Hours
Core Tip

Core Tip: Cirrhosis, characterized by progressive liver damage due to chronic injury, frequently induces changes in blood cell counts, functions, and coagulation abnormalities. Recognizing and understanding these alterations is pivotal as they often reflect the severity of liver disease. This knowledge enables healthcare providers to anticipate potential complications, initiate timely interventions, and tailor treatment strategies for patients with cirrhosis. This review aims to summarize available data on the prevalence of these abnormalities, delve into their pathophysiology, and elucidate their implications for patient management.