Rocahepevirus ratti: An underrecognised cause of acute hepatitis

doi:10.4254/wjh.v16.i8.1084

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 27, 2024; 16(8): 1084-1090
Published online Aug 27, 2024. doi: 10.4254/wjh.v16.i8.1084

Rocahepevirus ratti: An underrecognised cause of acute hepatitis

George S Gherlan

George S Gherlan, Department of Infectious Diseases, “Carol Davila” University of Medicine and Pharmacy, Bucharest 050474, Romania

Author contributions: Gherlan GS designed the overall concept and outline of the manuscript; He also wrote and edited the manuscript, created the illustrations, and reviewed the literature.

Conflict-of-interest statement: The author has no conflict of interest to declare.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: George S Gherlan, MD, PhD, Lecturer, Department of Infectious Diseases, “Carol Davila” University of Medicine and Pharmacy, 281 Mihai Bravu Street, Bucharest 050474, Romania. george.gherlan@umfcd.ro

Received: May 25, 2024
Revised: July 25, 2024
Accepted: July 30, 2024
Published online: August 27, 2024
Processing time: 88 Days and 17.5 Hours

Core Tip

Core Tip: Zoonoses are increasingly encountered in human pathology as the human/animal interface becomes closer and deeper. Rocahepevirus ratti, a virus related to the human hepatitis E virus but genetically highly divergent, has demonstrated the ability to cross species barriers and cause infections in humans. These infections, ranging from subclinical to severe and even life-threatening, are considered by many as an emerging threat to public health. The potential severity of Rocahepevirus ratti infections underscores the urgent need for improved diagnosis, treatment, and public health measures, as described in this editorial.