Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jul 27, 2024; 16(7): 1029-1038
Published online Jul 27, 2024. doi: 10.4254/wjh.v16.i7.1029
Trends of autoimmune liver disease inpatient hospitalization and mortality from 2011 to 2017: A United States nationwide analysis
Ali Wakil, Yasameen Muzahim, Mina Awadallah, Vikash Kumar, Natale Mazzaferro, Patricia Greenberg, Nikolaos Pyrsopoulos
Ali Wakil, Vikash Kumar, Department of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Brooklyn, NY 11201, United States
Yasameen Muzahim, Department of Gastroenterology and Hepatology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United States
Mina Awadallah, Nikolaos Pyrsopoulos, Department of Gastroenterology and Hepatology, Rutgers the New Jersey Medical School, Newark, NJ 07103, United States
Natale Mazzaferro, Patricia Greenberg, Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ 08854, United States
Author contributions: Wakil A, Muzahim Y, Awadallah M, Kumar V conducted research conceptualization, manuscript writing, analyzed the data and drew conclusion; Mazzaferro N, Greenberg P conducted research methodology, statistical analysis, data analysis; Pyrsopoulos N conducted research supervision and proofreading.
Institutional review board statement: This study was done using the National Inpatient Sample database which does not require approval from the institutional review board, thus no institutional review board approval was needed for this study.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data using National Inpatient Sample database which contains no identifying patient information and does not require informed consent to use the data.
Conflict-of-interest statement: All authors have no conflict of interest.
Data sharing statement: Statistical code, and dataset available from the corresponding author at pyrsopni@njms.rutgers.edu. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nikolaos Pyrsopoulos, FAASLD, MD, Professor, Department of Gastroenterology and Hepatology, Rutgers New Jersey Medical School, 150 Bergen Street, Newark, NJ 07103, United States. pyrsopni@njms.rutgers.edu
Received: April 6, 2024
Revised: May 23, 2024
Accepted: June 25, 2024
Published online: July 27, 2024
Processing time: 110 Days and 16.5 Hours
Core Tip

Core Tip: This study revealed a notable decline in the number of hospitalizations due to autoimmune liver disease (AiLD) across the United States, alongside an overall increase in the associated costs and financial burden. The findings offer valuable data for future prospective research, which could lead to more proactive screening efforts in outpatient settings to identify patients with AiLD earlier.