Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jul 27, 2024; 16(7): 1018-1028
Published online Jul 27, 2024. doi: 10.4254/wjh.v16.i7.1018
Liver stiffness in hepatocellular carcinoma and chronic hepatitis patients: Hepatitis B virus infection and transaminases should be considered
Jia-Yao Huang, Jian-Yun Peng, Hai-Yi Long, Xian Zhong, Yu-Hua Xie, Lu Yao, Xiao-Yan Xie, Man-Xia Lin
Jia-Yao Huang, Jian-Yun Peng, Hai-Yi Long, Xian Zhong, Yu-Hua Xie, Lu Yao, Xiao-Yan Xie, Man-Xia Lin, Department of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
Author contributions: Huang JY and Lin MX designed the research study; Huang JY, Peng JY, Long HY, Zhong X, Xie YH, Yao L, Xie XY and Lin MX collected the cases in the study; Huang JY, Peng JY, Long HY, Zhong X, Xie YH, Yao L, Xie XY and Lin MX performed the research; Huang JY and Lin MX analyzed the data; Huang JY and Lin MX wrote the manuscript; All authors have read and approved the final manuscript.
Supported by Natural Science Foundation of Guangdong Province, No. 2023A1515012464 and No. 2022A1515011716; and Basic and Applied Basic Research Foundation of Guangdong Province, No. 2022A1515110666.
Institutional review board statement: The protocol of this single-center retrospective study was in accordance with the Declaration of Helsinki (as revised in 2013) and was approved by the Institutional Review Board of the First Affiliated Hospital of Sun Yat-sen University (Approval No. [2019]046).
Informed consent statement: The need for written informed consent was waived for the retrospective analysis.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The data that support the findings of this study are available from the corresponding author (linmxia@mail.sysu.edu.cn) upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Man-Xia Lin, PhD, Doctor, Professor, Department of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan Road II, Yuexiu District, Guangzhou 510080, Guangdong Province, China. linmxia@mail.sysu.edu.cn
Received: March 23, 2024
Revised: May 27, 2024
Accepted: June 27, 2024
Published online: July 27, 2024
Processing time: 124 Days and 23 Hours
Core Tip

Core Tip: Liver stiffness measurement by two-dimensional shear wave elastography was significantly correlated with most liver condition indices in patients with chronic hepatitis B and hepatocellular carcinoma, but these correlations varied according to differences in hepatitis virus DNA and transaminase concentrations.