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World J Hepatol. Feb 27, 2024; 16(2): 186-192
Published online Feb 27, 2024. doi: 10.4254/wjh.v16.i2.186
Recent advances in the diagnosis of drug-induced liver injury
Taqwa Ahmed, Jawad Ahmad
Taqwa Ahmed, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States
Jawad Ahmad, Department of Recanati-Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States
Author contributions: Ahmed T and Ahmad J contributed equally to this work; All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jawad Ahmad, FAASLD, FRCP, MD, Professor, Department of Recanati-Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, United States. jawad.ahmad@mountsinai.org
Received: September 29, 2023
Peer-review started: October 1, 2023
First decision: November 7, 2023
Revised: January 3, 2024
Accepted: February 3, 2024
Article in press: February 3, 2024
Published online: February 27, 2024
Core Tip

Core Tip: Diagnosing drug induced liver injury (DILI) remains a challenge in the absence of a reliable biomarker. This review highlights some of the recent advances in causality assessment in DILI that will allow clinicians to be more certain in making a diagnosis.