Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2024; 16(12): 1417-1428
Published online Dec 27, 2024. doi: 10.4254/wjh.v16.i12.1417
Clinicopathological presentation of liver abscesses and hydatid liver disease from two South African tertiary hospitals
Krevosha Pillay, Zafar Ahmed Khan, Ekene Emmanuel Nweke, Jones Omoshoro-Jones
Krevosha Pillay, Zafar Ahmed Khan, Ekene Emmanuel Nweke, Jones Omoshoro-Jones, Department of Surgery, University of Witwatersrand, School of Clinical Medicine, Johannesburg 2193, Gauteng, South Africa
Zafar Ahmed Khan, Jones Omoshoro-Jones, Department of Hepatobiliary Surgery, Chris Hani Baragwanath Academic Hospital, Soweto 1864, Gauteng, South Africa
Author contributions: Omoshoro-Jones J and Pillay K contributed to study design; Pillay K and Khan ZA contributed to data acquisition and analysis; Pillay K drafted the manuscript; Omoshoro-Jones J, Khan ZA, and Nweke EE contributed to manuscript review and revision.
Institutional review board statement: This study was reviewed and approved by the Human Research Ethics Committee of the University of Witwatersrand.
Informed consent statement: This was a retrospective review of an administrative database, thus informed consent was not obtained.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Krevosha Pillay, MBChB, MMed, Lecturer, Surgeon, Department of Surgery, University of Witwatersrand, School of Clinical Medicine, 7 York Road, Johannesburg 2193, Gauteng, South Africa. krevoshap@gmail.com
Received: April 17, 2024
Revised: October 2, 2024
Accepted: October 29, 2024
Published online: December 27, 2024
Processing time: 225 Days and 20.3 Hours
Core Tip

Core Tip: The incidence, etiology, and microbiology of liver abscesses vary across geographical areas. There is a paucity of published data evaluating liver abscesses and hydatid liver disease in Sub Saharan Africa. HIV and diabetes mellitus were major comorbidities, highlighting immunosuppression as an important factor in the pathogenesis of infective liver collections. The majority of patients were managed non-operatively, with surgery reserved for complications. The small number of hydatid disease cases in this study made it difficult to draw significant conclusions in this group of patients, and further prospective studies are required.